Material Safety Data Sheet
Styrene Monomer, Inhibited

ACC# 22100
Section 1 - Chemical Product and Company Identification

MSDS Name: Styrene Monomer, Inhibited
Catalog Numbers: O4507-1
Synonyms:
Ethenylbenzene; Cinnamene; Cinnamenol; Ethenylbenzene; Phenethylene; Styrol; Vinylbenzene; Vinylbenzol
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
100-42-5 Styrene >99.0 202-851-5

Hazard Symbols:
XN
Risk Phrases:
10 36/38 20

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: clear, colorless. Flash Point: 88 deg F. Warning! Flammable liquid and vapor. Aspiration hazard if swallowed. Can enter lungs and cause damage. May cause eye and skin irritation. May cause respiratory and digestive tract irritation. May cause central nervous system depression. May cause reproductive and fetal effects. May cause cancer based on animal studies. Uninhibited material may form explosive peroxides.
Target Organs: Central nervous system.


Potential Health Effects
Eye: Causes eye irritation.
Skin: May be absorbed through the skin in harmful amounts. Prolonged and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May cause central nervous system depression, characterized by excitement, followed by headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness, coma and possible death due to respiratory failure. Aspiration of material into the lungs may cause chemical pneumonitis, which may be fatal.
Inhalation: Aspiration may cause respiratory swelling and pneumonitis. Causes narcotic effects including headache, dizziness, weakness, unconsciousness, and possible death.
Chronic: No information found.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin: Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. If conscious drink water, then induce vomiting. If unconscious, immediately take victim to a physician and do NOT attempt to induce vomiting.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Notes to Physician: Treat symptomatically
Antidote: None reported.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Vapors may form an explosive mixture with air. Flammable Liquid. Can release vapors that form explosive mixtures at temperatures above the flashpoint. Containers may explode in the heat of a fire.
Extinguishing Media: This material is lighter than water and insoluble in water. The fire could easily be spread by the use of water in an area where the water cannot be contained. Use water fog, dry chemical, carbon dioxide, or regular foam.

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Clean up spills immediately, observing precautions in the Protective Equipment section. Use a spark-proof tool. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well-ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with skin and eyes. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Take precautionary measures against static discharges. Avoid ingestion and inhalation. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from sources of ignition. Store in a cool place in the original container and protect from sunlight. Keep refrigerated. (Store below 4C/39F.) Keep containers tightly closed.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Styrene 20 ppm TWA; 40 ppm STEL 50 ppm TWA; 215 mg/m3 TWA 700 ppm IDLH 100 ppm TWA; C 200 ppm

OSHA Vacated PELs: Styrene: 50 ppm TWA; 215 mg/m3 TWA; 100 ppm STEL; 425 mg/m3 STEL
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties


Physical State: Liquid
Appearance: clear, colorless
Odor: pungent odor
pH: Not available.
Vapor Pressure: 568 mm Hg
Vapor Density: 1.22 Kg/m3
Evaporation Rate:0.5 (Butyl Acetate=1)
Viscosity: 0.751 mPa
Boiling Point: 293 deg F
Freezing/Melting Point:-23 deg F
Autoignition Temperature: 914 deg F ( 490.00 deg C)
Flash Point: 88 deg F ( 31.11 deg C)
Decomposition Temperature:Not available.
NFPA Rating: (estimated) Health: 2; Flammability: 3; Reactivity: 2
Explosion Limits, Lower:1.1% v/v
Upper: 7.0% v/v
Solubility: Practically insoluble in water
Specific Gravity/Density:0.9060
Molecular Formula:C8 H8
Molecular Weight:104.1

Section 10 - Stability and Reactivity


Chemical Stability: Stable under normal temperatures and pressures. May form peroxides in the absence of inhibitors.
Conditions to Avoid: Incompatible materials, ignition sources.
Incompatibilities with Other Materials: Vapor is explosive when exposed to heat or flame and reacts with oxygen at temperatures above 104 F, unhibited material may form explosive peroxides. Uninhibited material may polymerize which becomes self-sustaining at temperatures above 65 C. Exposure to butyllithium, dibenzoyl peroxide, azoisobutyronitrile or di-tert-butylperoxide may cause violent polymerization. Violent reaction with chlorosulfonic acid, oleum, sulfuric acid and oxidizers. Oxygen + heat is explosive.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.

Section 11 - Toxicological Information


RTECS#:
CAS# 100-42-5: WL3675000
LD50/LC50:
CAS# 100-42-5:
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit, eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 100% Moderate;
Inhalation, mouse: LC50 = 9500 mg/m3/4H;
Inhalation, rat: LC50 = 12 gm/m3/4H;
Oral, mouse: LD50 = 316 mg/kg;
Oral, rat: LD50 = 2650 mg/kg;
Carcinogenicity:
CAS# 100-42-5:
ACGIH: A4 - Not Classifiable as a Human Carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: TCLo (Inhalation, rat) = 293 ppm/6H; Reproductive - Effects on Newborn - behavioral.
Teratogenicity: TCLo - Lowest published toxic concentration(Inhalation,rat)= 300 ppm/6H; Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi; Lungs, Thorax, or Respiration - other changes; Liver - other changes.
Reproductive Effects: RTECs reports reproductive effects in animals such as effects on weaning/lactation index, naternal effects, fetoxitity, stillbirth and post-implantation mortality. TCLo (Inhalation, rat) = 293 ppm/6H; Reproductive - Effects on Newborn - behavioral.
Neurotoxicity: No information available.
Mutagenicity: An increased incidence of mutations such as chromosome aberrations and micronuclei in peripheral lymphocytes has been reported in workers exposed occupationally. Some studies have found a slight increase in the incidence of sister chromatid exchanges while no increase has been found in several other studies.Mutation in microorganisms(Salmonella typhimurium) =1 umol/plate(Yeast - Saccharomyces cerevisiae) =1 mmol/L.
Other Studies: IARC has determined that there is inadequate evidence for carcinogenicity in humans. Three studies have sugg ested an association between leukaemia and lymph omas with exposure to styrene. Other studies have sh own no excess in mortality from cancer in humans. IARC has determined there is sufficient evidence of carcinogen icity in animals.Standard Draize test(skin,rabbit) = 100%; Moderate.Standard Draize test(eye,rabbit) = 100 mg; Severe.

Section 12 - Ecological Information


Ecotoxicity: No data available. Cas# 100-42-5:LC50(96Hr.)Fathead Minnow = 46.4` mg/L; Static Bioassay Softwater.LC50(96Hr.)Fathead Minnow = 59.30 mg/L; Static Bioassay, Hardwater.LC50(96Hr.)Bluegill = 25.05 mg/L; Static Bioassay, Softwater.LC50(96Hr.)Goldfish = 64.74 mg/L; Static Bioassay, water.LC50(48Hr.) Water flea = 23.0 mg/L, Unspecified Bioassay.EC50(48Hr.) Water flea = 23.0 mg/L; Unspecified Bioassay.
Environmental: Styrene does not absorb solar radiation at wavelengths above the solar cutoff (approximately 300 nm); therefore, it will not be directly photolyzed in the lower atmosphere (troposphere) or surface water. However, styrene is expected to be involved in indirect photochemical reactions. Styrenes have been found to be very active generators of photochemical smog.
Physical: Styrene released to soil is subject to biodegradation. Volatilization and biodegradation are important transport and degradation processes respectively for styrene in water.
Other: No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name: No information available. STYRENE MONOMER
Hazard Class: 3(9.2)
UN Number: UN2055
Packing Group: III
Additional Info: FLASHPOINT 31C

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 100-42-5 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

Section 302 (RQ)
CAS# 100-42-5: final RQ = 1000 pounds (454 kg)
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 100-42-5: acute, chronic, flammable, reactive.
Section 313
This material contains Styrene (CAS# 100-42-5, 99 0%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 100-42-5 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 100-42-5 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 100-42-5 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:

R 10 Flammable.
R 36/38 Irritating to eyes and skin.
R 20 Harmful by inhalation.

Safety Phrases:

S 23 Do not inhale gas/fumes/vapour/spray.

WGK (Water Danger/Protection)

CAS# 100-42-5: 2
Canada
CAS# 100-42-5 is listed on Canada's DSL List. CAS# 100-42-5 is listed on Canada's DSL List.
This product has a WHMIS classification of B2, D2A, F.
CAS# 100-42-5 is listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 100-42-5: OEL-AUSTRALIA:TWA 50 ppm (215 mg/m3);STEL 100 ppm (42
5 mg/m3) OEL-BELGIUM:TWA 50 ppm (213 mg/m3);STEL 100 ppm (426 mg/m3);
Skin OEL-CZECHOSLOVAKIA:TWA 200 mg/m3;STEL 1000 mg/m3 OEL-DENMARK:TW
A 25 ppm (105 mg/m3) OEL-FINLAND:TWA 20 ppm (85 mg/m3);STEL 100 ppm (
420 mg/m3) OEL-FRANCE:TWA 50 ppm (215 mg/m3) OEL-GERMANY:TWA 20 ppm
(85 mg/m3) OEL-HUNGARY:STEL 50 mg/m3;Carcinogen OEL-JAPAN:TWA 50 ppm
(210 mg/m3) OEL-THE NETHERLANDS:TWA 100 ppm (420 mg/m3) OEL-THE PHI
LIPPINES:TWA 100 ppm (420 mg/m3) OEL-POLAND:TWA 100 mg/m3 OEL-SWEDEN
:TWA 25 ppm (110 mg/m3);STEL 75 ppm (30 mg/m3);Skin OEL-SWITZERLAND:T
WA 50 ppm (215 mg/m3);STEL 100 ppm (430 mg/m3) OEL-THAILAND:TWA 100 p
pm;STEL 200 ppm OEL-TURKEY:TWA 100 ppm (420 mg/m3) OEL-UNITED KINGDO
M:TWA 100 ppm (420 mg/m3);STEL 260 ppm OEL IN BULGARIA, COLOMBIA, JOR
DAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM che
ck ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 4/28/1999
Revision #2 Date: 8/02/2000
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.