Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Salicylic Acid
Catalog Numbers: S78056, S78056-1, A275, A275-12, A275-212,
A275-500, A275250LB, A277 500, A277-500, A277500, NC9747210, S780561,
Synonyms: Benzoic acid, 2-hydroxy-; o-Hydroxybenzoic
acid; 2-Hydroxybenzoic acid; Orthohydroxybenzoic acid
Fair Lawn, NJ 07410
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
Risk Phrases: 22 36/38
Section 3 - Hazards
Appearance: white. Warning! Contact with skin causes
irritation and possible burns, especially if the skin is wet or moist. Light
sensitive. Moisture sensitive. May be harmful if swallowed. May cause central
nervous system effects. Causes severe eye irritation. May cause reproductive and
fetal effects. Causes digestive and respiratory tract irritation.
Target Organs: Kidneys, central nervous system, pancreas.
Potential Health Effects
Eye: Causes severe eye irritation. May result in
Skin: Contact with skin causes irritation
and possible burns, especially if the skin is wet or moist. If absorbed, may
cause symptoms similar to those for ingestion. May cause skin rash and
Ingestion: Causes gastrointestinal irritation
with nausea, vomiting and diarrhea. May cause "salicylism"; characterized by
headache, dizziness, ringing in the ears, hearing difficulty, visual
disturbances, mental confusion, drowsiness, sweating thirst, hyperventilation,
nausea, vomiting and diarrhea. May be harmful if swallowed. Severe salicylate
intoxication may cause central nervous system disturbances such as convulsions
and coma, skin eruptions, and alteration in the acid-base balance.
Inhalation: Causes irritation of the mucous membrane and
upper respiratory tract.
Chronic: May cause reproductive
and fetal effects. Laboratory experiments have resulted in mutagenic effects.
May cause salicylism with effects similar to those of skin absorption. May cause
damage to the kidneys and pancrease.
Section 4 - First Aid
Eyes: Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid immediately.
Skin: Get medical aid immediately.
Immediately flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion: If victim is conscious and alert, give 2-4
cupfuls of milk or water. Never give anything by mouth to an unconscious person.
Get medical aid. Induce vomiting by giving one teaspoon of Syrup of Ipecac.
Inhalation: Get medical aid immediately. Remove from
exposure to fresh air immediately. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen.
Physician: Follow with gastric lavage with activated charcoal. If
available, administer ferric hexacyanoferrate as a gastrointestinal trapping
agent. Persons with pre-existing skin disorders, eye problems, or impaired
kidney function may be more susceptible to the effects of this substance.
Section 5 - Fire
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Dusts at sufficient concentrations can form explosive mixtures with air.
During a fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion.
Extinguishing Media: For small
fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam.
Water or foam may cause frothing. Use agent most appropriate to extinguish fire.
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Vacuum or sweep up material and
place into a suitable disposal container. Avoid generating dusty conditions.
Remove all sources of ignition. Provide ventilation.
Section 7 - Handling
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use only in a well-ventilated area.
Minimize dust generation and accumulation. Avoid contact with eyes, skin, and
clothing. Avoid ingestion and inhalation.
away from sources of ignition. Do not store in direct sunlight. Store in a cool,
dry, well-ventilated area away from incompatible substances. Store protected
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
OSHA Vacated PELs:
Salicylic acid: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Wear appropriate protective eyeglasses or chemical safety goggles as described
by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European
Skin: Wear appropriate protective gloves to
prevent skin exposure.
Clothing: Wear appropriate
protective clothing to prevent skin exposure.
respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2
requirements or European Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
Section 9 - Physical
and Chemical Properties
Odor: odorless -
slight phenolic odor
Vapor Pressure: 0.000082 mm
Vapor Density: No data
Viscosity: Not available.
Boiling Point: 211 deg C @
Freezing/Melting Point:158 - 160 deg C
Temperature: 535 deg C ( 995.00 deg F)
Flash Point: 157 deg C (
314.60 deg F)
Decomposition Temperature:Not available.
Rating: (estimated) Health: 0; Flammability: 1; Reactivity: 0
Explosion Limits, Lower:1.1 % @ 392F
Upper: Not available.
Section 10 -
Stability and Reactivity
Stability: Stable under normal temperatures and pressures. Moisture
sensitive. Light sensitive. Darkens on exposure to light.
Avoid: High temperatures, incompatible materials, light, moisture, strong
Incompatibilities with Other Materials: Oxidizing agents,
lead acetate, iron salts, alkalis, iodine, spirit nitrous ether.
Hazardous Decomposition Products: Carbon monoxide, irritating and
toxic fumes and gases, carbon dioxide.
Hazardous Polymerization: Will
Section 11 -
CAS# 69-72-7: VO0525000
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit,
skin: 500 mg/24H Mild;
Inhalation, rat: LC50 = >900 mg/m3/1H;
mouse: LD50 = 480 mg/kg;
Oral, rabbit: LD50 = 1300 mg/kg;
Oral, rat: LD50
= 891 mg/kg;
Skin, rabbit: LD50 = >10 gm/kg;
Skin, rat: LD50 = >2
CAS# 69-72-7: Not listed by ACGIH,
IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: Oral, rat: TDLo = 1050 mg/kg (female 8-14 day(s)
after conception) Specific Developmental Abnormalities - Central Nervous System
and craniofacial (including nose and tongue) and musculoskeletal system.; Oral,
rat: TDLo = 350 mg/kg (female 8-14 day(s) after conception) Effects on Embryo or
Fetus - extra-embryonic structures (e.g., placenta, umbilical cord).; Oral,
mouse: TDLo = 1 gm/kg (female 17 day(s) after conception) Fertility -
post-implantation mortality (e.g. dead and/or resorbed implants per total number
of implants) and fetotoxicity (except death, e.g., stunted fetus).
Reproductive Effects: Oral, rat: TDLo = 1050 mg/kg (female 8-14
day(s) after conception) Maternal Effects - uterus, cervix, vagina and Fertility
- post-implantation mortality (e.g. dead and/or resorbed implants per total
number of implants) and litter size (e.g. # fetuses per litter; measured before
birth).; Oral, rat: TDLo = 40 mg/kg (female 20-21 day(s) after conception)
Maternal Effects - parturition.
Neurotoxicity: No information
Mutagenicity: Mutation in Microorganisms: Saccharomyces
cerevisiae = 1 mmol/L/3H.; DNA Inhibition: Oral, mouse = 100 mg/kg.
Studies: Standard Draize Test: Administration onto the skin (rabbit) = 500
mg/24Hr (Mild). Standard Draize Test: Administrat ion into the eye (rabbit) =
100 mg (Severe).
Section 12 -
Bacteria: Phytobacterium phosphoreum: EC50 = 214 mg/L; 5 min; Microtox test
Adsorption, volatilization and bioconcentration are not expected to be important
environmental fate processes. Biodegradation is expected to be the dominant
removal mechanism from soil and water. It may also undergo photochemical
degradation in sunlit environmental media.
Environmental: In air, it
is expected to exist in both the vapor and particulate phase. Vapor phase
reaction with photochemically produced hydroxyl radicals may be important
(estimated half-life of 1.2 days). Removal by wet and dry deposition can also
occur. BOD = 141%, 5 days.
Physical: Rapidly degrades to phenol when
Other: Dangerous to aquatic life in high concentrations.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 -
||No information available.
||No information available.|
Section 15 -
CAS# 69-72-7 is listed on the TSCA
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
None of the chemicals in this product are under a Chemical Test
None of the chemicals are listed under TSCA
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
None of the chemicals in this material have an RQ.
None of the chemicals in this product have a TPQ.
CAS # 69-72-7: acute, chronic.
chemicals are reportable under Section 313.
Clean Air Act:
material does not contain any hazardous air pollutants. This material does not
contain any Class 1 Ozone depletors. This material does not contain any Class 2
Clean Water Act:
None of the chemicals in this
product are listed as Hazardous Substances under the CWA. None of the chemicals
in this product are listed as Priority Pollutants under the CWA. None of the
chemicals in this product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product are considered highly
hazardous by OSHA.
CAS# 69-72-7 is not present on state
lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level:
None of the chemicals in this product are listed. European/International
European Labeling in Accordance with EC
Harmful if swallowed.
R 36/38 Irritating to eyes and skin.
S 26 In case of contact with eyes, rinse immediately
plenty of water and seek medical advice.
S 28 After contact with skin, wash
S 39 Wear eye/face protection.
CAS# 69-72-7: 1
CAS# 69-72-7 is
listed on Canada's DSL List. CAS# 69-72-7 is listed on Canada's DSL List.
This product has a WHMIS classification of D2B.
CAS# 69-72-7 is listed
on Canada's Ingredient Disclosure List.
Section 16 -
MSDS Creation Date:
Revision #1 Date: 8/02/2000
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.