Material Safety Data Sheet
p-Dichlorobenzene

ACC# 17640
Section 1 - Chemical Product and Company Identification

MSDS Name: p-Dichlorobenzene
Catalog Numbers: S79996, S79996-1, S79996-2, S799961, S799962, B249 3, B249-3, B2493, NC9854048, XXB24925KG
Synonyms:
p-DCB; 1,4-Dichlorobenzene; Dichlorocide, Paracide; Paradichlorobenzol; p-Chlorophenyl chloride.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
106-46-7 P-Dichlorobenzene >99% 203-400-5

Hazard Symbols:
XN
Risk Phrases:
22 36/38

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white solid. Flash Point: 150 deg F. Warning! May cause liver and kidney damage. May cause blood abnormalities. May be harmful if inhaled. Harmful if swallowed. Causes respiratory tract irritation. May cause digestive tract irritation. Cancer suspect agent. May cause cancer based on animal studies. Causes eye and skin irritation.
Target Organs: Blood, kidneys, liver.


Potential Health Effects
Eye: Causes eye irritation. Exposure to high vapor concentrations may cause irritation.
Skin: Solid produces burning sensation when held in contact with the skin, but irritation is slight.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver and kidney damage.
Inhalation: Causes respiratory tract irritation. May cause liver and kidney damage. Inhalation of vapors causes irritation of eyes, throat, and skin. Exposure may cause anorexia, nausea, vomiting, weight loss and hepatic necrosis with jaundice. Exposure may cause headache and rhinitis (inflammation of the mucous membrane of the nose).
Chronic: Overexposure may cause delayed kidney injury. Possible cancer hazard based on tests with laboratory animals. Chronic ingestion may cause liver damage. May cause anemia and other blood cell abnormalities.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. Use water spray to keep fire-exposed containers cool.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.
Flash Point: 150e deg F ( 65.56 deg C)
Autoignition Temperature: 640 deg C ( 1,184.00 deg F)
Explosion Limits, Lower:1.7
Upper: 12.0
NFPA Rating: (estimated) Health: 2; Flammability: 2; Instability: 0

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Avoid generating dusty conditions. Remove all sources of ignition. Carefully scoop up and place into appropriate disposal container.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Storage: Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Use adequate general or local exhaust ventilation to keep airborne concentrations below the permissible exposure limits.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
P-Dichlorobenzene 10 ppm TWA 150 ppm IDLH 75 ppm TWA; 450 mg/m3 TWA

OSHA Vacated PELs: P-Dichlorobenzene: 75 ppm TWA; 450 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: white
Odor: moth-powder odor
pH: Not available.
Vapor Pressure: 1.18 mm Hg @25C
Vapor Density: 5.07 (air=1)
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 345 deg F
Freezing/Melting Point:127.6 deg F
Decomposition Temperature:Not available.
Solubility: Insoluble in water.
Specific Gravity/Density:1.5 (water=1)
Molecular Formula:C6H4Cl2
Molecular Weight:146.934

Section 10 - Stability and Reactivity


Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions.
Conditions to Avoid: High temperatures, incompatible materials, ignition sources, dust generation.
Incompatibilities with Other Materials: Aluminum, oxidizing agents.
Hazardous Decomposition Products: Hydrogen chloride, chlorine, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:
CAS# 106-46-7: CZ4550000
LD50/LC50:
CAS# 106-46-7:
Oral, mouse: LD50 = 2950 mg/kg;
Oral, rabbit: LD50 = 2830 mg/kg;
Oral, rat: LD50 = 500 mg/kg;
Skin, rabbit: LD50 = >2 gm/kg;
Skin, rat: LD50 = >6 gm/kg;
Carcinogenicity:
CAS# 106-46-7:
ACGIH: A3 - Animal Carcinogen
California: carcinogen; initial date 1/1/89
NIOSH: potential occupational carcinogen
NTP: Suspect carcinogen
OSHA: Possible Select carcinogen
IARC: Group 2B carcinogen
Epidemiology: IARC has determined that the human data are inadequate to ev aluate the carcinogenicity of dichlorobenzenes.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: None.

Section 12 - Ecological Information


Ecotoxicity: No data available. Fish (fresh water) 50ppm lethal (no time interval specified) Rainbow trout (fresh water) TLm= 880mg/48H
Environmental: Substance can be adsorbed in soil, and leaching is possible. Substance is volatile from water, but has potential for sediment adsorption.
Physical: Substance (in soil and water) has low probability for chemical transformation by hydrolysis, oxidation, or direct photolysis.
Other: Please refer to the Handbook of Environmental Fate and Exposure Data (Vol I) for additional information.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 106-46-7: waste number U072.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name: No information available. No information available.
Hazard Class:
UN Number:
Packing Group:

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 106-46-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

CERCLA Hazardous Substances and corresponding RQs
CAS# 106-46-7: 100 lb final RQ; 45.4 kg final RQ
SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 106-46-7: acute, chronic, flammable.
Section 313
This material contains P-Dichlorobenzene (CAS# 106-46-7, 99%),which is subject to the reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 106-46-7 is listed as a hazardous air pollutant (HAP). This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 106-46-7 is listed as a Hazardous Substance under the CWA. CAS# 106-46-7 is listed as a Priority Pollutant under the Clean Water Act. CAS# 106-46-7 is listed as a Toxic Pollutant under the Clean Water Act.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 106-46-7 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Minnesota, Massachusetts.
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act: WARNING: This product contains P-Dichlorobenzene, a chemical known to the state of California to cause cancer. California No Significant Risk Level: CAS# 106-46-7: 20 ug/day NSRL

European/International Regulations

European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:

R 22 Harmful if swallowed.
R 36/38 Irritating to eyes and skin.

Safety Phrases:

S 22 Do not breathe dust.
S 24/25 Avoid contact with skin and eyes.
S 46 If swallowed, seek medical advice immediately
and show this container or label.

WGK (Water Danger/Protection)

CAS# 106-46-7: 2
Canada - DSL/NDSL
CAS# 106-46-7 is listed on Canada's DSL List.
Canada - WHMIS
This product has a WHMIS classification of B3, D1B, D2A.
Canadian Ingredient Disclosure List
CAS# 106-46-7 is listed on the Canadian Ingredient Disclosure List.
Exposure Limits
CAS# 106-46-7: OEL-AUSTRALIA:TWA 75 ppm (450 mg/m3);STEL 110 ppm (67
5 mg/m3) OEL-BELGIUM:TWA 75 ppm (451 mg/m3);STEL 110 ppm (661 mg/m3)
OEL-DENMARK:TWA 75 ppm (450 mg/m3) OEL-FINLAND:TWA 75 ppm (450 mg/m3
);STEL 115 ppm (690 mg/m3);Skin OEL-FRANCE:TWA 75 ppm (450 mg/m3);STE
L 110 ppm (675 mg/m3) OEL-GERMANY:TWA 75 ppm (450 mg/m3) OEL-JAPAN:T
WA 50 ppm (300 mg/m3) OEL-THE NETHERLANDS:TWA 75 ppm (450 mg/m3) OEL
-THE PHILIPPINES:TWA 75 ppm (450 mg/m3) OEL-POLAND:TWA 20 mg/m3 OEL-
RUSSIA:TWA 50 ppm OEL-SWEDEN:TWA 75 ppm (450 mg/m3);STEL 110 ppm (700
mg/m3) OEL-SWITZERLAND:TWA 75 ppm (450 mg/m3);STEL 150 ppm (900 mg/m
3) OEL-TURKEY:TWA 75 ppm (450 mg/m3) OEL-UNITED KINGDOM:TWA 75 ppm (
450 mg/m3);STEL 11 ppm OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check
ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #3 Date: 3/18/2003

The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.