Ninhydrin



**** MATERIAL SAFETY DATA SHEET ****

Ninhydrin
16500

**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Ninhydrin
Catalog Numbers:
T349 10
Synonyms:
2,2-Dihydroxy-1,3-indandione; Triketohydrindene Hydrate.
Company Identification: Fisher Scientific
1 Reagent Lane
Fairlawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300

**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+------------+------------------------------------+---------+-----------+
| CAS# | Chemical Name | % | Einecs# |
|------------|------------------------------------|---------|-----------|
| 485-47-2|1h-indene-1,3(2h)-dione, 2,2-dihydro|>95 |207-618-1 |
xy-
+------------+------------------------------------+---------+-----------+

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Appearance: White to off-white crystals or powder.
Target Organs: None.

Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation.
Ingestion:
May cause gastrointestinal irritation with nausea, vomiting and
diarrhea.
Inhalation:
May cause respiratory tract irritation.
Chronic:
No information found.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids.
Get medical aid.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes.
Get medical aid if irritation develops or persists.
Ingestion:
Do NOT induce vomiting.
If victim is conscious and alert, give 2-4 cupfuls of milk or water.
Get medical aid immediately.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear.
Dusts at sufficient concentrations can form explosive mixtures with
air.
Combustible solid.
Extinguishing Media:
Use water spray, dry chemical, or carbon dioxide.
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Explosion Limits, Lower: Not available.
Upper: Not available.

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equpiment as indicated
in Section 8.
Spills/Leaks:
Sweep up, then place into a suitable clean, dry container for
disposal. Avoid generating dusty conditions.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash hands before eating.
Use with adequate ventilation.
Minimize dust generation and accumulation.
Avoid contact with skin and eyes.
Keep container tightly closed.
Do not ingest or inhale.
Storage:
Keep from contact with oxidizing materials.
Store in a cool, dry, well-ventilated area away from incompatible
substances.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.

Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name | ACGIH | NIOSH |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| 1h-indene-1,3(2h)-d|none listed |none listed |none listed |
| ione, 2,2-dihydroxy| | | |
| - | | | |
+--------------------+-------------------+-------------------+-----------------+

OSHA Vacated PELs:
1h-indene-1,3(2h)-dione, 2,2-dihydroxy-:
No OSHA Vacated PELs are listed for this chemical.

Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133.
Skin:
Wear appropriate protective gloves to prevent skin
exposure.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1010.134. Always use a NIOSH-approved respirator when
necessary.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Solid
Appearance: White to off-white crystals or powder.
Odor: Odorless.
pH: Not available.
Vapor Pressure: Negligible.
Vapor Density: 6.16 (air=1)
Evaporation Rate: Not applicable.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 464_F
Decomposition Temperature: 464_F
Solubility: Soluble in water.
Specific Gravity/Density: Not available.
Molecular Formula: C9H6O4
Molecular Weight: 178.0396

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable under normal temperatures and pressures.
Conditions to Avoid:
High temperatures, incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizers.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 485-47-2: NK5425000
LD50/LC50:
CAS# 485-47-2.
Carcinogenicity:
1h-indene-1,3(2h)-dione, 2,2-dihydroxy- -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Neurotoxicity:
No information available.
Mutagenicity:
No information available.
Other Studies:
None.

**** SECTION 12 - ECOLOGICAL INFORMATION ****

Ecotoxicity:
No information available.
Environmental Fate:
No information available.
Physical/Chemical:
No information available.
Physical/Chemical:
None.

**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants: Not listed.
RCRA D-Series Chronic Toxicity Reference Levels: Not listed.
RCRA F-Series: Not listed.
RCRA P-Series: Not listed.
RCRA U-Series: Not listed.
Not listed as a material banned from land disposal according to RCRA.

**** SECTION 14 - TRANSPORT INFORMATION ****

US DOT
No information available
IMO
No information available.
IATA
No information available.
RID/ADR
No information available.
Canadian TDG
No information available.

**** SECTION 15 - REGULATORY INFORMATION ****

A. Federal
TSCA
CAS# 485-47-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA/SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous
Substances under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
B. State
Not present on state lists from CA, PA, MN, MA, FL, or NJ.
California No Significant Risk Level:
None of the chemicals in this product are listed.
C. International
Canada
CAS# 485-47-2 is listed on Canada's DSL/NDSL List.
CAS# 485-47-2 is not listed on Canada's Ingredient Disclosure List.
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
Exposure Limits:
OEL-RUSSIA:STEL 0.1 mg/m3

**** SECTION 16 - ADDITIONAL INFORMATION ****

Additional Information:
No additional information available.
MSDS Creation Date: June 8, 1995
The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes.
--------------------------------------------------------------------------------
MSDS INDEX