Material Safety Data
Methyl Alcohol, Reagent ACS, 99.8% (GC)
MSDS Name: Methyl Alcohol, Reagent ACS, 99.8% (GC)
Section 1 - Chemical Product and Company
Catalog Numbers: AC423950000, AC423950010, AC423950020, AC423955000,
Synonyms: Carbinol; Methanol; Methyl hydroxide;
Monohydroxymethane; Pyroxylic spirit; Wood alcohol; Wood naptha; Wood spirit;
Monohydroxymethane; Methyl hydrate.
Acros Organics N.V.
One Reagent Lane
Fair Lawn, NJ 07410
For information in North
America, call: 800-ACROS-01
For emergencies in the US, call
Section 2 -
Composition, Information on Ingredients
Symbols: T F
Risk Phrases: 11 23/24/25 39/23/24/25
Section 3 - Hazards
Appearance: clear, colorless. Flash Point: 11 deg C. Poison! Cannot be made
non-poisonous. Causes eye and skin irritation. May be absorbed through intact
skin. This substance has caused adverse reproductive and fetal effects in
animals. Danger! Flammable liquid
and vapor. Harmful if inhaled. May be fatal or cause blindness if swallowed.
May cause central nervous system depression. May cause digestive tract
irritation with nausea, vomiting, and diarrhea. Causes respiratory tract
irritation. May cause liver, kidney and heart damage.
Kidneys, heart, central nervous system, liver, eyes.
Potential Health Effects
Eye: Produces irritation, characterized by a burning
sensation, redness, tearing, inflammation, and possible corneal injury. May
cause painful sensitization to light.
Skin: Causes moderate
skin irritation. May be absorbed through the skin in harmful amounts. Prolonged
and/or repeated contact may cause defatting of the skin and dermatitis.
Ingestion: May be fatal or cause blindness if swallowed.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May
cause systemic toxicity with acidosis. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness,
drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness,
coma and possible death due to respiratory failure. May cause cardiopulmonary
Inhalation: Harmful if inhaled. May cause
adverse central nervous system effects including headache, convulsions, and
possible death. May cause visual impairment and possible permanent blindness.
Causes irritation of the mucous membrane.
Prolonged or repeated skin contact may cause dermatitis. Chronic inhalation and
ingestion may cause effects similar to those of acute inhalation and ingestion.
Chronic exposure may cause reproductive disorders and teratogenic effects.
Laboratory experiments have resulted in mutagenic effects. Prolonged exposure
may cause liver, kidney, and heart damage.
Section 4 - First Aid
Eyes: Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid immediately.
Skin: Immediately flush skin with
plenty of soap and water for at least 15 minutes while removing contaminated
clothing and shoes. Get medical aid if irritation develops or persists. Wash
clothing before reuse.
Ingestion: If victim is conscious
and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately. Induce vomiting by giving one
teaspoon of Syrup of Ipecac.
Inhalation: Get medical aid
immediately. Remove from exposure to fresh air immediately. If breathing is
difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing
has ceased apply artificial respiration using oxygen and a suitable mechanical
device such as a bag and a mask.
Notes to Physician:
Effects may be delayed. Ethanol may inhibit methanol metabolism.
Section 5 - Fire
Information: Containers can build up pressure if exposed to heat and/or
fire. As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Water runoff can cause environmental damage. Dike and collect water used to
fight fire. Vapors can travel to a source of ignition and flash back. During a
fire, irritating and highly toxic gases may be generated by thermal
decomposition or combustion. Flammable Liquid. Can release vapors that form
explosive mixtures at temperatures above the flashpoint. Use water spray to keep
fire-exposed containers cool. Water may be ineffective. Material is lighter than
water and a fire may be spread by the use of water. Vapors may be heavier than
air. They can spread along the ground and collect in low or confined areas. May
be ignited by heat, sparks, and flame.
For small fires, use dry chemical, carbon dioxide, water spray or
alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water
may be ineffective. For large fires, use water spray, fog or alcohol-resistant
foam. Do NOT use straight streams of water.
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Scoop up with a nonsparking tool,
then place into a suitable container for disposal. Use water spray to disperse
the gas/vapor. Remove all sources of ignition. Absorb spill using an absorbent,
non-combustible material such as earth, sand, or vermiculite. Do not use
combustible materials such as saw dust. Provide ventilation. A vapor suppressing
foam may be used to reduce vapors. Water spray may reduce vapor but may not
prevent ignition in closed spaces.
Section 7 - Handling
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Ground and bond containers when
transferring material. Do not breathe dust, vapor, mist, or gas. Do not get in
eyes, on skin, or on clothing. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Keep container tightly closed. Avoid
contact with heat, sparks and flame. Do not ingest or inhale. Use only in a
chemical fume hood. Do not pressurize, cut, weld, braze, solder, drill, grind,
or expose empty containers to heat, sparks or open flames.
Storage: Keep away from heat, sparks, and flame. Keep away
from sources of ignition. Store in a cool, dry, well-ventilated area away from
incompatible substances. Flammables-area. Keep containers tightly closed. Do not
store in aluminum or lead containers.
Section 8 - Exposure
Controls, Personal Protection
Controls: Use explosion-proof ventilation equipment. Facilities storing
or utilizing this material should be equipped with an eyewash facility and a
safety shower. Use adequate general or local exhaust ventilation to keep
airborne concentrations below the permissible exposure limits. Use only under a
chemical fume hood.
||200 ppm TWA; 250 ppm STEL; skin - potential for cutaneous
||200 ppm TWA; 260 mg/m3 TWA 6000 ppm IDLH
||200 ppm TWA; 260 mg/m3
OSHA Vacated PELs: Methyl
alcohol: 200 ppm TWA; 260 mg/m3 TWA; 250 ppm STEL; 325 mg/m3 STEL
Personal Protective Equipment
Wear chemical goggles.
Skin: Wear appropriate protective
gloves to prevent skin exposure.
Clothing: Wear appropriate
protective clothing to prevent skin exposure.
respiratory protection program that meets OSHA's 29 CFR §1910.134 and ANSI Z88.2
requirements or European Standard EN 149 must be followed whenever workplace
conditions warrant a respirator's use.
Section 9 - Physical
and Chemical Properties
Appearance: clear, colorless
Odor: alcohol-like -
pH: Not available.
Vapor Pressure: 128 mm Hg @
20 deg C
Vapor Density: 1.11 (Air=1)
Viscosity: 0.55 cP 20 deg C
Boiling Point: 64.7
deg C @ 760.00mm Hg
Freezing/Melting Point:-98 deg C
Autoignition Temperature: 464 deg C ( 867.20 deg F)
Point: 11 deg C ( 51.80 deg F)
NFPA Rating: (estimated) Health: 1; Flammability: 3;
Explosion Limits, Lower:6.0 vol %
36.00 vol %
Section 10 -
Stability and Reactivity
Stability: Stable under normal temperatures and pressures.
to Avoid: High temperatures, incompatible materials, ignition sources,
Incompatibilities with Other Materials: Acids (mineral,
non-oxidizing, e.g. hydrochloric acid, hydrofluoric acid, muriatic acid,
phosphoric acid), acids (mineral, oxidizing, e.g. chromic acid, hypochlorous
acid, nitric acid, sulfuric acid), acids (organic, e.g. acetic acid, benzoic
acid, formic acid, methanoic acid, oxalic acid), azo, diazo, and hydrazines
(e.g. dimethyl hydrazine, hydrazine, methyl hydrazine), isocyanates (e.g. methyl
isocyanate), nitrides (e.g. potassium nitride, sodium nitride), peroxides and
hydroperoxides (organic, e.g. acetyl peroxide, benzoyl peroxide, butyl peroxide,
methyl ethyl ketone peroxide), epoxides (e.g. butyl glycidyl ether), Oxidants
(such as barium perchlorate, bromine, chlorine, hydrogen peroxide, lead
perchlorate, perchloric acid, sodium hypochlorite)., Active metals (such as
potassium and magnesium)., acetyl bromide, alkyl aluminum salts, beryllium
dihydride, carbontetrachloride, carbon tetrachloride + metals, chloroform +
heat, chloroform + sodium hydroxide, cyanuric chloride, diethyl zinc, nitric
acid, potassium-tert-butoxide, chloroform + hydroxide, water reactive substances
(e.g. acetic anyhdride, alkyl aluminum chloride, calcium carbide, ethyl
Hazardous Decomposition Products: Carbon monoxide,
irritating and toxic fumes and gases, carbon dioxide, formaldehyde.
Hazardous Polymerization: Will not occur.
Section 11 -
CAS# 67-56-1: PC1400000
Draize test, rabbit, eye: 40 mg Moderate;
Draize test, rabbit,
eye: 100 mg/24H Moderate;
Draize test, rabbit, skin: 20 mg/24H
Inhalation, rat: LC50 = 64000 ppm/4H;
Oral, mouse: LD50 = 7300
Oral, rabbit: LD50 = 14200 mg/kg;
Oral, rat: LD50 = 5628
Skin, rabbit: LD50 = 15800 mg/kg;
CAS# 67-56-1: Not listed by ACGIH, IARC, NIOSH,
NTP, or OSHA.
Epidemiology: Methanol has been shown to produce
fetotoxicity in the embr yo or fetus of laboratory animals. Specific
developmenta l abnormalities include cardiovascular, musculoskeletal, and
Teratogenicity: Effects on Newborn: Behaviorial,
Oral, rat: TDLo=7500 mg/kg (female 17-19 days after conception). Effects on
Embryo or Fetus: Fetotoxicity, Inhalation, rat: TCLo=10000 ppm/7H (female 7-15
days after conception). Specific Developmental Abnormalities: Cardiovascular,
Musculoskeletal, Urogenital, Inhalation, rat: TCLo=20000 ppm/7H (7-14 days after
Reproductive Effects: Paternal Effects: Spermatogenesis:
Intraperitoneal, mouse TDLo=5 g/kg ( male 5 days pre-mating). Fertility: Oral,
rat: TDLo = 35295 mg/kg (female 1-15 days after conception). Paternal Effects:
Testes, Epididymis, Sperm duct: Oral, rat: TDLo = 200 ppm/20H (male 78 weeks
Neurotoxicity: No information available.
Mutagenicity: DNA inhibition: Human Lymphocyte = 300 mmol/L. DNA
damage: Oral, rat = 10 umol/kg. Mutation in microorganisms: Mouse Lymphocyte =
7900 mg/L. Cytogenetic analysis: Oral, mouse = 1 gm/kg.
Studies: Standard Draize Test(Skin, rabbit) = 20 mg/24H (Moderate) S tandard
Draize Test: Administration into the eye (rabbit) = 40 mg (Moderate). Standard
Draize test: Administration int o the eye (rabbit) = 100 mg/24H (Moderate).
Section 12 -
Fish: Fathead Minnow: 29.4 g/L; 96 Hr; LC50 (unspecified) Goldfish: 250 ppm; 11
Hr; resulted in death Rainbow trout: 8000 mg/L; 48 Hr; LC50 (unspecified)
Rainbow trout: LC50 = 13-68 mg/L; 96 Hr.; 12 degrees C Fathead Minnow: LC50 =
29400 mg/L; 96 Hr.; 25 degrees C, pH 7.63 Rainbow trout: LC50 = 8000 mg/L; 48
Hr.; Unspecified ria: Phytobacterium phosphoreum: EC50 = 51,000-320,000 mg/L; 30
minutes; Microtox test No data available.
Environmental: Dangerous to
aquatic life in high concentrations. Aquatic toxicity rating: TLm 96>1000
ppm. May be dangerous if it enters water intakes. Methyl alcohol is expected to
biodegrade in soil and water very rapidly. This product will show high soil
mobility and will be degraded from the ambient atmosphere by the reaction with
photochemically produced hyroxyl radicals with an estimated half-life of 17.8
days. Bioconcentration factor for fish (golden ide) < 10. Based on a log Kow
of -0.77, the BCF value for methanol can be estimated to be 0.2.
Physical: No information available.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-56-1:
waste number U154; (Ignitable waste).
Section 14 -
||FLASHPOINT 11 C|
Section 15 -
CAS# 67-56-1 is listed on the TSCA
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
None of the chemicals in this product are under a Chemical Test
None of the chemicals are listed under TSCA
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
CAS# 67-56-1: final RQ = 5000 pounds (2270 kg)
None of the chemicals in this product have a TPQ.
CAS # 67-56-1: acute, flammable.
material contains Methyl alcohol (CAS# 67-56-1, 99%),which is subject to the
reporting requirements of Section 313 of SARA Title III and 40 CFR Part 373.
Clean Air Act:
CAS# 67-56-1 is listed as a hazardous air pollutant
(HAP). This material does not contain any Class 1 Ozone depletors. This material
does not contain any Class 2 Ozone depletors.
None of the chemicals in this product are listed as Hazardous
Substances under the CWA. None of the chemicals in this product are listed as
Priority Pollutants under the CWA. None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
None of the
chemicals in this product are considered highly hazardous by OSHA.
CAS# 67-56-1 can be found on the following state right to
know lists: California, New Jersey, Florida, Pennsylvania, Minnesota,
California No Significant Risk Level: None of the chemicals
in this product are listed. European/International
European Labeling in Accordance with EC
R 23/24/25 Toxic by inhalation, in contact with skin
and if swallowed.
R 39/23/24/25 Toxic : danger of very serious
irreversible effects through inhalation, in contact
with skin and if
S 16 Keep away from sources of
ignition - No
S 36/37 Wear suitable protective clothing and
S 45 In case of accident or if you feel unwell, seek
advice immediately (show the label where
S 7 Keep container
WGK (Water Danger/Protection)
CAS# 67-56-1: 1
CAS# 67-56-1 is listed on Canada's DSL List. CAS# 67-56-1
is listed on Canada's DSL List.
This product has a WHMIS classification of
B2, D1A, D2B.
CAS# 67-56-1 is listed on Canada's Ingredient Disclosure List.
CAS# 67-56-1: OEL-ARAB Republic of Egypt:TWA 200
ppm (260 mg/m3);Ski
n OEL-AUSTRALIA:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin
M:TWA 200 ppm (262 mg/m3);STEL 250 ppm;Skin OEL-CZECHOSLOVAKIA:TWA
0 mg/m3;STEL 500 mg/m3 OEL-DENMARK:TWA 200 ppm (260 mg/m3);Skin
FINLAND:TWA 200 ppm (260 mg/m3);STEL 250 ppm;Skin OEL-FRANCE:TWA 200
ppm (260 mg/m3);STEL 1000 ppm (1300 mg/m3) OEL-GERMANY:TWA 200 ppm (2
mg/m3);Skin OEL-HUNGARY:TWA 50 mg/m3;STEL 100 mg/m3;Skin JAN9 OEL
200 ppm (260 mg/m3);Skin OEL-THE NETHERLANDS:TWA 200 ppm (
OEL-THE PHILIPPINES:TWA 200 ppm (260 mg/m3) OEL-POLA
ND:TWA 100 mg/m3
OEL-RUSSIA:TWA 200 ppm;STEL 5 mg/m3;Skin OEL-SWEDEN
:TWA 200 ppm (250
mg/m3);STEL 250 ppm (350 mg/m3);Skin OEL-SWITZERLAN
D:TWA 200 ppm (260
mg/m3);STEL 400 ppm;Skin OEL-THAILAND:TWA 200 ppm
(260 mg/m3) OEL-TURKEY:TWA
200 ppm (260 mg/m3) OEL-UNITED KINGDOM:TW
A 200 ppm (260 mg/m3);STEL 250
ppm;Skin OEL IN BULGARIA, COLOMBIA, JO
RDAN, KOREA check ACGIH TLV OEL IN NEW
ZEALAND, SINGAPORE, VIETNAM ch
eck ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #4 Date: 3/14/2001
The information above is
believed to be accurate and represents the best information currently available
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