Material Safety Data Sheet
Maleic Acid

ACC# 13550
Section 1 - Chemical Product and Company Identification

MSDS Name: Maleic Acid
Catalog Numbers: O3417 500, O3417-500, O3417500, S80068, S80068-1
Synonyms:
cis-Butenedioic Acid; cis-1,2-Ethylenedicarboxylic Acid; Hydroxysuccinic Acid; Maleinic Acid; Toxilic Acid.
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
110-16-7 Maleic acid >98.0 203-742-5

Hazard Symbols:
XN
Risk Phrases:
22 36/37/38

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white. Danger! May cause kidney damage. May cause severe digestive tract irritation with possible burns. May be harmful if swallowed or absorbed through the skin. Causes eye and skin irritation and possible burns. Causes respiratory tract irritation and possible burns.
Target Organs: Kidneys.


Potential Health Effects
Eye: May result in corneal injury. Contact with eyes may cause severe irritation, and possible eye burns.
Skin: Contact with skin causes irritation and possible burns, especially if the skin is wet or moist. May cause dermatitis. May be harmful if absorbed through the skin.
Ingestion: May cause severe and permanent damage to the digestive tract. Causes gastrointestinal tract burns. May cause kidney damage. May be harmful if swallowed.
Inhalation: May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema. Causes chemical burns to the respiratory tract.
Chronic: Overexposure may cause delayed kidney injury.

Section 4 - First Aid Measures


Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed. Extensive irrigation with water is required (at least 30 minutes).
Skin: Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Ingestion: Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Do NOT use mouth-to-mouth resuscitation. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. May accumulate static electrical charges, and may cause ignition of its own vapors. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Wear a self contained breathing apparatus and appropriate Personal protection. (See Exposure Controls, Personal Protection section). Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Use with adequate ventilation. Discard contaminated shoes.
Storage: Keep away from sources of ignition. Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances. Corrosives area.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Maleic acid none listed none listed none listed

OSHA Vacated PELs: Maleic acid: No OSHA Vacated PELs are listed for this chemical.
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: white
Odor: faint, acidulous odor
pH: <7 (acidic)
Vapor Pressure: Negligible.
Vapor Density: Not applicable.
Evaporation Rate:Negligible.
Viscosity: Not available.
Boiling Point: 275 deg F
Freezing/Melting Point:266 deg F
Autoignition Temperature: Not applicable.
Flash Point: Not applicable.
Decomposition Temperature:275 deg F
NFPA Rating: (estimated) Health: 3; Flammability: 1; Reactivity: 1
Explosion Limits, Lower:Not available.
Upper: Not available.
Solubility: 79% @ 20C in water.
Specific Gravity/Density:1.59 (water=1)
Molecular Formula:C4H4O4
Molecular Weight:116.0256

Section 10 - Stability and Reactivity


Chemical Stability: Stable. However, may decompose if heated.
Conditions to Avoid: Incompatible materials, dust generation, temperatures above 200C.
Incompatibilities with Other Materials: Strong oxidizing agents, strong reducing agents, strong bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: May occur.

Section 11 - Toxicological Information


RTECS#:
CAS# 110-16-7: OM9625000
LD50/LC50:
CAS# 110-16-7:
Draize test, rabbit, eye: 100 mg Severe;
Draize test, rabbit, eye: 1%/2M Severe;
Draize test, rabbit, skin: 500 mg/24H Mild;
Inhalation, rat: LC50 = >720 mg/m3/1H;
Oral, mouse: LD50 = 2400 mg/kg;
Oral, rat: LD50 = 708 mg/kg;
Skin, rabbit: LD50 = 1560 mg/kg;
Carcinogenicity:
CAS# 110-16-7: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information available.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
Mutagenicity: No information available.
Other Studies: See actual entry in RTECS for complete information.

Section 12 - Ecological Information


Ecotoxicity: Fish: Fathead Minnow: LC50 = 5 mg/L; 96 Hr.; Unspecified Mosquito Fish: LC50 = 240 mg/L; 24-48 Hr.; Unspecified No data available.
Environmental: If released on land, maleic acid will leach into the ground and probably biodegrade. While maleic acid is readily biodegraded, no degradability data were found for soil systems. If released into water, maleic acid will probably biodegrade based on the results of screening studies. No biodegradability studies were found in environmental waters. Adsorption to sediment and volatilization should not be significant.
Physical: Due to its polar nature, maleic acid released into the atmosphere will be primarily associated with aerosols. It will be subject to gravitational settling and also degrade by reaction with ozone and photochemically produced hydroxyl radicals (half-life 1.1 hr).
Other: The BCF of maleic acid in fish (golden ide) was <10 after 3 days of exposure while that in algae (Chorella fusca) was 11 after 24hr. The BCF calculated from the water solubility (788 g/l) using a reommended regression equation is 3, which indicates the bioconcentration should not be an important process.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name: MALEIC ACID MALEIC ACID
Hazard Class: 8 8(9.2)
UN Number: NA2215 UN2215
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 110-16-7 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

Section 302 (RQ)
CAS# 110-16-7: final RQ = 5000 pounds (2270 kg)
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 110-16-7: acute.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 110-16-7 is listed as a Hazardous Substance under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 110-16-7 can be found on the following state right to know lists: California, New Jersey, Pennsylvania, Massachusetts.
California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:

R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.

Safety Phrases:

S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...
S 37 Wear suitable gloves.

WGK (Water Danger/Protection)

CAS# 110-16-7: 1
Canada
CAS# 110-16-7 is listed on Canada's DSL List. CAS# 110-16-7 is listed on Canada's DSL List.
This product has a WHMIS classification of E.
CAS# 110-16-7 is listed on Canada's Ingredient Disclosure List.
Exposure Limits

Section 16 - Additional Information

MSDS Creation Date: 6/03/1999
Revision #1 Date: 8/02/2000
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.