Cyclohexane

**** MATERIAL SAFETY DATA SHEET ****

Cyclohexane
05870

**** SECTION 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION ****

MSDS Name: Cyclohexane
Catalog Numbers:
C552-1, C553 4, C553-4, C555 1, C555 4, C555-1, C555-4, C556 1, C556 4,
C556 500, C556-1, C556-4, C556-500, C620 1, C620 4, C620-1, C620-4,
C620SK 1, C620SK 4, C620SK-1, C620SK-4, O2093 20, O2093 4, O2093-20,
O2093-4, S79990, S79990-1, S79990HPLC, S79990SPEC-1, S79990SPEC-2
Synonyms:
Benzene hexahydride, hexahydrobenzene, hexamethylene,
hexanaphthalene.
Company Identification: Fisher Scientific
1 Reagent Lane
Fairlawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300

**** SECTION 2 - COMPOSITION, INFORMATION ON INGREDIENTS ****

+------------+------------------------------------+---------+-----------+
| CAS# | Chemical Name | % | EINECS# |
|------------|------------------------------------|---------|-----------|
| 110-82-7|Cyclohexane |>99% |unlisted |
+------------+------------------------------------+---------+-----------+

**** SECTION 3 - HAZARDS IDENTIFICATION ****

EMERGENCY OVERVIEW
Appearance: Colorless liquid. Flash Point: -4_F.
DANGER! EXTREMELY FLAMMABLE LIQUID. MAY CAUSE CENTRAL NERVOUS SYSTEM
DEPRESSION. ASPIRATION HAZARD. MAY CAUSE EYE AND SKIN IRRITATION. MAY
CAUSE RESPIRATORY AND DIGESTIVE TRACT IRRITATION. MAY CAUSE LIVER AND
KIDNEY DAMAGE.
Target Organs: Kidneys, central nervous system, liver, cardiovascular
system.

Potential Health Effects
Eye:
May cause mild eye irritation.
Skin:
May be absorbed through the skin in harmful amounts. May cause
irritation with burning pain, itching and redness.
Ingestion:
Ingestion of large amounts may cause gastrointestinal irritation.
May cause liver and kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache,
dizziness, drowsiness, and nausea. Advanced stages may cause
collapse, unconsciousness, coma and possible death due to
respiratory failure. May cause vascular collapse and damage.
Aspiration of material into the lungs may cause chemical pneumonitis,
which may be fatal.
Inhalation:
Inhalation of high concentrations may cause central nervous system
effects characterized by headache, dizziness, unconsciousness and
coma. May cause respiratory tract irritation. May be fatal if exposed
to high concentrations.
Chronic:
Prolonged or repeated skin contact may cause defatting and
dermatitis.

**** SECTION 4 - FIRST AID MEASURES ****

Eyes:
Flush eyes with plenty of water for at least 15 minutes,
occasionally lifting the upper and lower lids. Get medical aid. Do
NOT allow victim to rub or keep eyes closed.
Skin:
Flush skin with plenty of soap and water for at least 15 minutes
while removing contaminated clothing and shoes. Get medical aid if
irritation develops or persists.
Ingestion:
Do NOT induce vomiting. Possible aspiration hazard. Get medical aid
immediately.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing,
give artificial respiration. If breathing is difficult, give oxygen.
Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.
No specific antidote exists.

**** SECTION 5 - FIRE FIGHTING MEASURES ****

General Information:
As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full
protective gear. Vapors can travel to a source of ignition and flash
back. Extremely flammable. Material will readily ignite at room
temperature. Use water spray to keep fire-exposed containers cool.
Extinguishing Media:
Use foam, dry chemical, or carbon dioxide. Water may be ineffective.
This material is lighter than water and insoluble in water. The fire
could easily be spread by the use of water in an area where the
water cannot be contained.
Autoignition Temperature: 473_F (245.00_C)
Flash Point: -4_F (-17.78_C)
NFPA Rating: health-1; flammability-3; reactivity-0
Explosion Limits, Lower: 1.3
Upper: 8.0

**** SECTION 6 - ACCIDENTAL RELEASE MEASURES ****

General Information: Use proper personal protective equipment as indicated
in Section 8.
Spills/Leaks:
Absorb spill with inert material, (e.g., dry sand or earth), then
place into a chemical waste container. Avoid runoff into storm
sewers and ditches which lead to waterways. Wear a self contained
breathing apparatus and appropriate Personal protection. (See
Exposure Controls, Personal Protection section). Scoop up with a
nonsparking tool, then place into a suitable container for disposal.
Remove all sources of ignition.

**** SECTION 7 - HANDLING and STORAGE ****

Handling:
Wash thoroughly after handling. Remove contaminated clothing and
wash before reuse. Use only in a well ventilated area. Do not reuse
this container. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Do not pressurize, cut, weld,
braze, solder, drill, grind, or expose such containers to heat,
sparks or open flames. Keep container tightly closed. Avoid contact
with heat, sparks and flame. Do not get on skin or in eyes. Avoid
ingestion and inhalation.
Storage:
Store in a tightly closed container. Store in a cool, dry,
well-ventilated area away from incompatible substances.

**** SECTION 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION ****

Engineering Controls:
Use adequate general or local exhaust ventilation to keep airborne
concentrations below the permissible exposure limits.

Exposure Limits
+--------------------+-------------------+-------------------+-----------------+
| Chemical Name | ACGIH | NIOSH |OSHA - Final PELs|
|--------------------|-------------------|-------------------|-----------------|
| Cyclohexane |300 ppm ; 1030 |300 ppm TWA; 1050 |300 ppm TWA; 1050|
| | mg/m3 |mg/m3 TWA | mg/m3 TWA |
+--------------------+-------------------+-------------------+-----------------+

OSHA Vacated PELs:
Cyclohexane:
300 ppm TWA; 1050 mg/m3 TWA

Personal Protective Equipment

Eyes:
Wear appropriate protective eyeglasses or chemical
safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133.
Skin:
Wear neoprene gloves, apron, and/or clothing. Wear
nitrile-latex gloves, apron, and/or clothing.
Clothing:
Wear appropriate protective clothing to prevent skin
exposure.
Respirators:
Follow the OSHA respirator regulations found in 29CFR
1010.134. Always use a NIOSH-approved respirator when
necessary.

**** SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES ****

Physical State: Liquid
Appearance: Colorless liquid.
Odor: Sweet chloroform-like.
pH: Not available.
Vapor Pressure: 95 mm Hg
Vapor Density: 0.7786 at 68F.
Evaporation Rate: 6.1 (Butyl acetate=1)
Viscosity: 1.02 cP at 63F.
Boiling Point: 177.3_F
Freezing/Melting Point: 44_F
Decomposition Temperature: Not available.
Solubility: Practically insoluble in water.
Specific Gravity/Density: 0.8 (Water=1)
Molecular Formula: CH2(CH2)4CH2
Molecular Weight: 84.084

**** SECTION 10 - STABILITY AND REACTIVITY ****

Chemical Stability:
Stable at room temperature in closed containers under normal storage
and handling conditions.
Conditions to Avoid:
Incompatible materials, ignition sources.
Incompatibilities with Other Materials:
Incompatible with oxidizing materials.
Hazardous Decomposition Products:
Oxides of carbon.
Hazardous Polymerization: Has not been reported.

**** SECTION 11 - TOXICOLOGICAL INFORMATION ****

RTECS#:
CAS# 110-82-7: GU6300000
LD50/LC50:
CAS# 110-82-7: Oral, mouse: LD50 = 813 mg/kg; Oral, rat: LD50 =
12705 mg/kg.
Carcinogenicity:
Cyclohexane -
Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology:
No information available.
Teratogenicity:
No information available.
Reproductive Effects:
No information available.
Neurotoxicity:
No information available.
Mutagenicity:
DNA damage; E. coli, 10 umol/L
Other Studies:
None.

**** SECTION 12 - ECOLOGICAL INFORMATION ****

Ecotoxicity:
Fathead minnow, LC50=95 mg/L/1H at 18-22C. Bluegill, TLm=43-34
mg/L/24-96H Goldfish, TLm=42.3 mg/L/24-96H
Environmental Fate:
In air, substance reacts with hydroxyl radicals.
Physical/Chemical:
No information available.
Other:
None.

**** SECTION 13 - DISPOSAL CONSIDERATIONS ****

Dispose of in a manner consistent with federal, state, and local regulations.
RCRA D-Series Maximum Concentration of Contaminants: Not listed.
RCRA D-Series Chronic Toxicity Reference Levels: Not listed.
RCRA F-Series: Not listed.
RCRA P-Series: Not listed.
RCRA U-Series: waste number U056 (Ignitable waste)
This material is banned from land disposal according to RCRA.

**** SECTION 14 - TRANSPORT INFORMATION ****

US DOT
Shipping Name: CYCLOHEXANE
Hazard Class: 3
UN Number: UN1145
Packing Group: II
IMO
No information available.
IATA
No information available.
RID/ADR
No information available.
Canadian TDG
Shipping Name: CYCLOHEXANE
Hazard Class: 3(9.2)
UN Number: UN1145
Other Information: FLASHPOINT -20 C

**** SECTION 15 - REGULATORY INFORMATION ****

A. Federal
TSCA
CAS# 110-82-7 is listed on the TSCA inventory.
Health & Safety Reporting List
CAS# 110-82-7: Effective Date: December 19, 1985
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
CERCLA/SARA
Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
SARA Codes
CAS # 110-82-7: acute, chronic, flammable.
Section 313
This chemical is not at a high enough concentration to be reportable
under Section 313.
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants.
This material does not contain any Class 1 Ozone depletors.
This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 110-82-7 is listed as a Hazardous Substance under the CWA.
None of the chemicals in this product are listed as Priority
Pollutants under the CWA.
None of the chemicals in this product are listed as Toxic Pollutants
under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous
by OSHA.
B. State
Cyclohexane can be found on the following state right to know lists:
California, New Jersey, Florida, Pennsylvania, Minnesota,
Massachusetts.
California No Significant Risk Level:
None of the chemicals in this product are listed.
C. International
Canada
CAS# 110-82-7 is listed on Canada's DSL/NDSL List.
CAS# 110-82-7 is listed on Canada's Ingredient Disclosure List.
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
Exposure Limits:
OEL-AUSTRALIA:TWA 300 ppm (1050 mg/m3). OEL-AUSTRIA:TWA 300 ppm (1050
mg/m3). OEL-BELGIUM:TWA 300 ppm (1030 mg/m3). OEL-DENMARK:TWA 300 ppm
(1050 mg/m3). OEL-FINLAND:TWA 300 ppm (1050 mg/m3);STEL 375 ppm (1315
mg/m3). OEL-FRANCE:TWA 300 ppm (1050 mg/m3);STEL 375 ppm (1300 mg/m3)

1000 mg/m3. OEL-JAPAN:TWA 150 ppm (520 mg/m3). OEL-THE NETHERLANDS:TWA
300 ppm (1050 mg/m3) JAN9. OEL-THE PHILIPPINES:TWA 300 ppm (1050 mg/m
3) JAN9. OEL-POLAND:TWA 80 mg/m3. OEL-RUSSIA:TWA 150 ppm;STEL 80 mg/m3
. OEL-SWEDEN:TWA 300 ppm (1000 mg/m3);STEL 370 ppm (1300 mg/m3). OEL-S
WITZERLAND:TWA 300 ppm (1050 mg/m3);STEL 600 ppm. OEL-TURKEY:TWA 300 p
pm (1050 mg/m3). OEL-UNITED KINGDOM:TWA 300 ppm (1050 mg/m3);STEL 375
ppm. OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV. OEL IN
NEW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV

**** SECTION 16 - ADDITIONAL INFORMATION ****

Additional Information:
Added NFPA codes to Section 5. Added SARA classifications to Section
15.
Section 3, Emer Overview, added "DANGER!..".
Section 3, Emer Overview, added "EXTREMELY FLAMMABLE LIQUID...".
Section 3, Emer Overview, added "ASPIRATION HAZARD...".
Section 3, Emer Overview, added "MAY CAUSE RESPIRATORY AND
DIGESTIVE..".
Section 3, Emer Overview, added "MAY CAUSE EYE AND SKIN
IRRITATION...".
Section 3, Emer Overview, added "MAY CAUSE CENTRAL NERVOUS SYSTEM
DE..".
Section 3, Emer Overview, added "MAY CAUSE LIVER AND KIDNEY
DAMAGE...".
Section 3, Eye Effects, added "May cause mild eye irritation...".
Section 3, Skin Effects, added "May cause irritation with burning
p..".
Section 3, Skin Effects, added "May be absorbed through the skin
in..".
Section 3, Inhalation Effects, added "Inhalation of high
concentrations m..".
Section 3, Inhalation Effects, added "May cause respiratory tract
irritat..".
Section 3, Inhalation Effects, added "May be fatal if exposed to
high con..".
Section 3, Ingestion Effects, added "Ingestion of large amounts may
caus..".
Section 3, Ingestion Effects, added "May cause central nervous
system de..".
Section 3, Ingestion Effects, added "May cause liver and kidney
damage...".
Section 3, Ingestion Effects, added "May cause vascular collapse
and dam..".
Section 3, Ingestion Effects, added "Aspiration of material into
the lun..".
Section 3, Chronic Effects, added "Prolonged or repeated skin
contact..".
Section 4, Eye First Aid, added "Do NOT allow victim to rub or
keep..".
Section 4, Eye First Aid, added "Flush eyes with plenty of water
for..".
Section 4, Eye First Aid, added "Get medical aid...".
Section 4, Skin First Aid, added "Flush skin with plenty of soap
and..".
Section 4, Skin First Aid, added "Get medical aid if irritation
devel..".
Section 4, Inhalation First Aid, added "Remove from exposure to
fresh air i..".
Section 4, Inhalation First Aid, added "If not breathing, give
artificial r..".
Section 4, Inhalation First Aid, added "If breathing is difficult,
give oxy..".
Section 4, Inhalation First Aid, added "Get medical aid...".
Section 4, Ingestion First Aid, added "Do NOT induce vomiting...".
Section 4, Ingestion First Aid, added "Possible aspiration hazard...
".
Section 4, Ingestion First Aid, added "Get medical aid immediately..
.".
Section 5, Extinguishing Media, added "Use foam, dry chemical, or ca
rbon d..".
Section 5, Extinguishing Media, added "Water may be ineffective...".
Section 5, Extinguishing Media, added "This material is lighter than
water..".
Section 5, General Firefighting, added "Use water spray to keep fire
-expose..".
Section 5, General Firefighting, added "As in any fire, wear a self-
contain..".
Section 5, General Firefighting, added "Vapors can travel to a sourc
e of ig..".
Section 5, General Firefighting, added "Extremely flammable. Materia
l will..".
Section 6, Spills/Leaks, added "Wear a self contained breathing app.
.".
Section 6, Spills/Leaks, added "Scoop up with a nonsparking tool, t.
.".
Section 6, Spills/Leaks, added "Absorb spill with inert material, (.
.".
Section 6, Spills/Leaks, added "Avoid runoff into storm sewers and..
".
Section 6, Spills/Leaks, added "Remove all sources of ignition...".
Section 7, Handling, added "Wash thoroughly after handling...".
Section 7, Handling, added "Remove contaminated clothing and wa..".
Section 7, Handling, added "Use only in a well ventilated area...".
Section 7, Handling, added "Do not reuse this container...".
Section 7, Handling, added "Do not get on skin or in eyes...".
Section 7, Handling, added "Avoid ingestion and inhalation...".
Section 7, Handling, added "Keep container tightly closed...".
Section 7, Handling, added "Avoid contact with heat, sparks and..".
Section 7, Handling, added "Empty containers retain product res..".
Section 7, Storage, added "Store in a cool, dry, well-ventilat..".
Section 7, Storage, added "Store in a tightly closed container..".
Section 8, Engin. Controls, added "Use adequate general or local exh
au..".
Section 8, Eye Protection, added "Wear appropriate protective eyegla
s..".
Section 8, Skin Protection, added "Wear neoprene gloves, apron, and/
or..".
Section 8, Skin Protection, added "Wear nitrile-latex gloves, apron,
a..".
Section 8, Clothing, added "Wear appropriate protective clothin..".
MSDS Creation Date: 12/16/1994 Revision Date: 3/04/1996

The information above is believed to be accurate and represents the best
information currently available to us. However, we make no warranty of
merchantability or any other warranty, express or implied, with respect to
such information, and we assume no liability resulting from its use. Users
should make their own investigations to determine the suitability of the
information for their particular purposes. In no way shall Fisher be liable
for any claims, losses, or damages of any third party or for lost profits
or any special, indirect, incidental, consequential or exemplary
damages, howsoever arising, even if Fisher has been advised of
the possibility of such damages.
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