Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Cyclohexane
Catalog Numbers: AC406020040, AC425580000, AC425580040,
AC425580200, AC425585000, S79990, S79990-1, S79990HPLC, S79990SPEC-1,
S79990SPEC-2, C552-1, C553-4, C5534LC, C555-1, C555-4, C556-1, C556-4, C556-500,
C556J4, C620-1, C620-4, C620J4, C620SK-1, C620SK-4, O2093-20, O2093-4
Synonyms: Benzene Hexahydride; Hexahydrobenzene; Hexamethylene;
1 Reagent Lane
Fair Lawn, NJ 07410
For information, call: 201-796-7100
Emergency Number: 201-796-7100
For CHEMTREC assistance,
For International CHEMTREC assistance, call:
Section 2 -
Composition, Information on Ingredients
Symbols: XN F N
Risk Phrases: 11 38 50/53 65 67
Section 3 - Hazards
Appearance: colourless. Flash Point: -20 deg C. Danger!
Aspiration hazard if swallowed. Can enter lungs and cause damage. May cause
respiratory and digestive tract irritation. May cause eye and skin irritation.
May cause central nervous system depression. May cause liver and kidney damage.
Highly flammable. May form explosive peroxides.
Kidneys, central nervous system, liver, cardiovascular system.
Potential Health Effects
Eye: May cause mild eye irritation.
Skin: May be absorbed through the skin in harmful amounts.
May cause irritation with burning pain, itching and redness.
Ingestion: Ingestion of large amounts may cause
gastrointestinal irritation. May cause liver and kidney damage. May cause
central nervous system depression, characterized by excitement, followed by
headache, dizziness, drowsiness, and nausea. Advanced stages may cause collapse,
unconsciousness, coma and possible death due to respiratory failure. May cause
vascular collapse and damage. Aspiration of material into the lungs may cause
chemical pneumonitis, which may be fatal.
Inhalation of high concentrations may cause central nervous system effects
characterized by nausea, headache, dizziness, unconsciousness and coma. May
cause respiratory tract irritation. May be fatal if exposed to high
Chronic: Prolonged or repeated skin contact
may cause defatting and dermatitis. May cause liver and kidney damage.
Section 4 - First Aid
Eyes: Flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Do NOT allow victim to rub or keep eyes closed.
skin with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical aid if irritation develops or
persists. Wash clothing before reuse.
Ingestion: Do NOT
induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or
water. Never give anything by mouth to an unconscious person. Possible
aspiration hazard. Get medical aid immediately.
Remove from exposure to fresh air immediately. If breathing is difficult, give
oxygen. Get medical aid. Do NOT use mouth-to-mouth resuscitation. If breathing
has ceased apply artificial respiration using oxygen and a suitable mechanical
device such as a bag and a mask.
Notes to Physician: Treat
symptomatically and supportively.
Section 5 - Fire
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
gear. Vapors may form an explosive mixture with air. Vapors can travel to a
source of ignition and flash back. During a fire, irritating and highly toxic
gases may be generated by thermal decomposition or combustion. Extremely
flammable. Material will readily ignite at room temperature. Use water spray to
keep fire-exposed containers cool. Liquid will float and may reignite on the
surface of water. Vapors may be heavier than air. They can spread along the
ground and collect in low or confined areas. May polymerize explosively when
involved in a fire. Containers may explode when heated.
Extinguishing Media: Water may be ineffective. This
material is lighter than water and insoluble in water. The fire could easily be
spread by the use of water in an area where the water cannot be contained. Do
NOT use straight streams of water. For large fires, use water spray, fog or
regular foam. For small fires, use dry chemical, carbon dioxide, water spray or
regular foam. Cool containers with flooding quantities of water until well after
fire is out.
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Absorb spill with inert material
(e.g. vermiculite, sand or earth), then place in suitable container. Avoid
runoff into storm sewers and ditches which lead to waterways. Clean up spills
immediately, observing precautions in the Protective Equipment section. Wear a
self contained breathing apparatus and appropriate Personal protection. (See
Exposure Controls, Personal Protection section). Scoop up with a nonsparking
tool, then place into a suitable container for disposal. Remove all sources of
ignition. Provide ventilation.
Section 7 - Handling
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use only in a well-ventilated area.
Do not reuse this container. Empty containers retain product residue, (liquid
and/or vapor), and can be dangerous. Keep container tightly closed. Avoid
contact with heat, sparks and flame. Do not get on skin or in eyes. Avoid
ingestion and inhalation. Do not pressurize, cut, weld, braze, solder, drill,
grind, or expose empty containers to heat, sparks or open flames.
Storage: Store in a tightly closed container. Store in a
cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
||(300 ppm) TWA
||300 ppm TWA; 1050 mg/m3 TWA 1300 ppm IDLH (10
percent lower explosive limit)
||300 ppm TWA; 1050 mg/m3
OSHA Vacated PELs:
Cyclohexane: 300 ppm TWA; 1050 mg/m3 TWA
Eyes: Wear appropriate protective
eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear neoprene gloves, apron, and/or clothing. Wear
nitrile-latex gloves, apron, and/or clothing.
Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR
1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN
149 approved respirator when necessary.
Section 9 - Physical
and Chemical Properties
Odor: sweetish odor -
pH: Not available.
Vapor Pressure: 95 mm
Vapor Density: 2.90
Evaporation Rate:6.1 (Butyl
Viscosity: 1.02 cP at 63F.
Boiling Point: 80.7
Freezing/Melting Point:6.5 deg C
Temperature: 245 deg C ( 473.00 deg F)
Flash Point: -20 deg C (
-4.00 deg F)
Decomposition Temperature:Not available.
Rating: (estimated) Health: 1; Flammability: 3; Reactivity: 0
Explosion Limits, Lower:1.3
Solubility: Practically insoluble in water.
Section 10 -
Stability and Reactivity
Stability: Stable at room temperature in closed containers under normal
storage and handling conditions. Explosive peroxides may form on concentration.
Peroxides can be detonated by friction, impact, or heating. Peroxide formation
may occur in containers that have been opened and remain in storage. Normally
stable; however, on long term storage, materials containing similar functional
groups form peroxides of unknown stability.
Conditions to Avoid:
Incompatible materials, ignition sources, excess heat, oxidizers.
Incompatibilities with Other Materials: Strong oxidizing agents,
Hazardous Decomposition Products: Carbon monoxide,
irritating and toxic fumes and gases, carbon dioxide.
Polymerization: Has not been reported.
Section 11 -
CAS# 110-82-7: GU6300000
Oral, mouse: LD50 = 813 mg/kg;
Oral, rat: LD50 = 12705
CAS# 110-82-7: Not listed by
ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No information
Teratogenicity: No information available.
Reproductive Effects: No information available.
Neurotoxicity: No information available.
damage; E. coli, 10 umol/L
Other Studies: None.
Section 12 -
Fish: Fathead Minnow: LC50 = 117.0 mg/L; 96 Hr.; Static conditions
Bluegill/Sunfish: LC50 = 34.72 mg/L; 96 Hr.; 25 degrees C flea Daphnia: EC50 =
400.00 mg/L; 48 Hr.; Unspecified ria: Phytobacterium phosphoreum: EC50 = 227.00
mg/L; 5, 30 minutes; Microtox test No data available.
Atmospheric Fate: Cyclohexane is expected to partition to the atmosphere where
it will rapidly react with hydroxyl radicals. TERRESTRIAL FATE: If released on
land, cyclohexane will be lost through volatilization and should leach into the
ground. Cyclohexane is resistant to biodegradation but may biodegrade slowly in
the presence of other hydrocarbons that are themselves degraded. AQUATIC FATE:
Volatilization from water (estimated half-life 2 hr in a model river) should be
the most important fate process occuring in aquatic systems.
Physical: ATMOSPHERIC FATE: In the atmosphere, cyclohexane will
degrade by reaction with photochemically produced hydroxyl radicals (half-life
52 hr). The half-life is much faster under photochemical smog conditions with
half-lives as low as 6 hr being reported.
Other: No experimental data
are available on the bioconcentration of cyclohexane in aquatic organisms. Using
the octanol/water partition coefficient, 3.44, one can estimate a BCF of 242
using a recommended regression equation.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 110-82-7:
waste number U056; (Ignitable waste).
Section 14 -
||FLASHPOINT -20 C|
Section 15 -
CAS# 110-82-7 is listed on the TSCA
Health & Safety Reporting List
Effective Date: December 19, 1985; Sunset Date: Decembe r 19, 1995
Chemical Test Rules
None of the chemicals in this product are
under a Chemical Test Rule.
CAS# 110-82-7: 4/12b
TSCA Significant New Use Rule
None of the chemicals in this
material have a SNUR under TSCA.
CAS# 110-82-7: final RQ = 1000 pounds (454 kg)
None of the chemicals in this product have a TPQ.
CAS # 110-82-7: acute, chronic, flammable.
This material contains Cyclohexane (CAS# 110-82-7, 99%),which is
subject to the reporting requirements of Section 313 of SARA Title III and 40
CFR Part 373.
Clean Air Act:
This material does not contain any
hazardous air pollutants. This material does not contain any Class 1 Ozone
depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
CAS# 110-82-7 is listed as a Hazardous Substance
under the CWA. None of the chemicals in this product are listed as Priority
Pollutants under the CWA. None of the chemicals in this product are listed as
Toxic Pollutants under the CWA.
None of the chemicals in
this product are considered highly hazardous by OSHA.
110-82-7 can be found on the following state right to know lists: California,
New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
Significant Risk Level: None of the chemicals in this product are listed.
European Labeling in
Accordance with EC Directives
XN F N
R 11 Highly flammable.
R 38 Irritating to skin.
R 50/53 Very toxic to aquatic organisms; may cause
effects in the aquatic environment.
R 65 Harmful: may cause lung damage if
R 67 Vapors may cause drowsiness and dizziness.
S 16 Keep away from sources of ignition - No
33 Take precautionary measures against static
S 9 Keep
container in a well-ventilated place.
S 60 This material and/or its
container must be
disposed of as hazardous waste.
S 61 Avoid release to
the environment. Refer to
special instructions/Safety data sheets.
If swallowed, do not induce vomiting: seek
medical advice immediately and
show this container or
CAS# 110-82-7: 1
CAS# 110-82-7 is
listed on Canada's DSL List. CAS# 110-82-7 is listed on Canada's DSL List.
This product has a WHMIS classification of B2, D2B.
CAS# 110-82-7 is
listed on Canada's Ingredient Disclosure List.
CAS# 110-82-7: OEL-AUSTRALIA:TWA 300 ppm (1050 mg/m3)
WA 300 ppm (1050 mg/m3) OEL-BELGIUM:TWA 300 ppm (1030 mg/m3)
MARK:TWA 300 ppm (1050 mg/m3) OEL-FINLAND:TWA 300 ppm (1050
EL 375 ppm (1315 mg/m3) OEL-FRANCE:TWA 300 ppm (1050 mg/m3);STEL
ppm (1300 mg/m3) OEL-GERMANY:TWA 300 ppm (1050 mg/m3)
A 500 mg/m3;STEL 1000 mg/m3 OEL-JAPAN:TWA 150 ppm (520 mg/m3)
E NETHERLANDS:TWA 300 ppm (1050 mg/m3) JAN9 OEL-THE PHILIPPINES:TWA
00 ppm (1050 mg/m3) JAN9 OEL-POLAND:TWA 80 mg/m3 OEL-RUSSIA:TWA 150
ppm;STEL 80 mg/m3 OEL-SWEDEN:TWA 300 ppm (1000 mg/m3);STEL 370 ppm (1
mg/m3) OEL-SWITZERLAND:TWA 300 ppm (1050 mg/m3);STEL 600 ppm OEL
300 ppm (1050 mg/m3) OEL-UNITED KINGDOM:TWA 300 ppm (1050
mg/m3);STEL 375 ppm
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check A
CGIH TLV OEL IN NEW
ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #3 Date: 8/02/2000
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.