Material Safety Data
Acetylsalicylic Acid 99%
Section 1 - Chemical Product and Company
MSDS Name: Acetylsalicylic Acid 99%
Catalog Numbers: AC158180000, AC158185000, S79881
Synonyms: 2-Acetoxybenzole acid, acenterine, acesal, aceticyl,
acetisal, acetol, acetophen, asagran, aspirin, caprin
Fair Lawn, NJ 07410
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
||Acetylsalicylic acid (aspirin)
Risk Phrases: 22 36/37/38
Section 3 - Hazards
Appearance: white. May cause skin irritation. Causes respiratory tract
irritation. May cause respiratory and digestive tract irritation. May cause
severe eye irritation and possible injury. Warning! Toxic.
Harmful if swallowed.
Target Organs: Blood.
Potential Health Effects
Eye: May cause eye irritation and possible burns.
Skin: May cause skin irritation. Low hazard for usual
industrial handling. Chronic ingestion may result in salicylism which is
characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic
Ingestion: May cause gastrointestinal irritation
with nausea, vomiting and diarrhea. Inhibits platelet aggregation affecting
Inhalation: May cause respiratory tract
irritation. Can produce anaphylactic shock with even small doses.
Chronic: Chronic ingestion may result in salicylism which
is characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic
Section 4 - First Aid
Eyes: Immediately flush eyes with plenty of water
for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get
medical aid immediately.
Skin: Get medical aid. Flush skin
with plenty of soap and water for at least 15 minutes while removing
contaminated clothing and shoes.
Ingestion: If victim is
conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately.
If not breathing, give artificial respiration. If breathing is difficult, give
oxygen. Get medical aid.
Notes to Physician: Treat
symptomatically and supportively.
Section 5 - Fire
Information: As in any fire, wear a self-contained breathing apparatus
in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective
Extinguishing Media: For small fires, use water
spray, dry chemical, carbon dioxide or chemical foam.
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Vacuum or sweep up material and
place into a suitable disposal container. Avoid generating dusty conditions.
Section 7 - Handling
Handling: Wash thoroughly after handling. Use with
adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and
Storage: Store in a cool, dry place. Store in a
tightly closed container.
Section 8 - Exposure
Controls, Personal Protection
Controls: Good general ventilation should be sufficient to control
|Acetylsalicylic acid (aspirin)
||5 mg/m3 TWA
||5 mg/m3 TWA
OSHA Vacated PELs:
Acetylsalicylic acid (aspirin): 5 mg/m3 TWA
Eyes: Wear appropriate protective
eyeglasses or chemical safety goggles as described by OSHA's eye and face
protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: Follow the OSHA respirator
regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - Physical
and Chemical Properties
Vapor Pressure: Not applicable.
Evaporation Rate:Not applicable.
Boiling Point: Not available.
Point:138 - 140 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
NFPA Rating: Not published.
Upper: Not available.
2.5 G/L (15°C)
Specific Gravity/Density:Not available.
Section 10 -
Stability and Reactivity
Conditions to Avoid: Incompatible materials,
Incompatibilities with Other Materials: Strong
alkali, hydrolyzes in moist air, decomposes in hot water.
Decomposition Products: Carbon monoxide, carbon dioxide.
Polymerization: Has not been reported.
Section 11 -
CAS# 50-78-2: VO0700000
Oral, mouse: LD50 = 250 mg/kg;
Oral, rabbit: LD50 = 1010
Oral, rat: LD50 = 200 mg/kg;
CAS# 50-78-2: Not listed by ACGIH, IARC, NIOSH,
NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: No data available.
No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: No data
Section 12 -
No information available.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.
Section 14 -
||TOXIC SOLID, ORGANIC,N.O.S. (ACETYLSALICYLIC ACID)
||POISONOUS SOLID NOS (ACETYLSALICYLIC
Section 15 -
CAS# 50-78-2 is listed on the TSCA
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
None of the chemicals in this product are under a Chemical Test
None of the chemicals are listed under TSCA
TSCA Significant New Use Rule
None of the chemicals
in this material have a SNUR under TSCA.
None of the chemicals in this material have an RQ.
None of the chemicals in this product have a TPQ.
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air
pollutants. This material does not contain any Class 1 Ozone depletors. This
material does not contain any Class 2 Ozone depletors.
None of the chemicals in this product are listed as Hazardous
Substances under the CWA. None of the chemicals in this product are listed as
Priority Pollutants under the CWA. None of the chemicals in this product are
listed as Toxic Pollutants under the CWA.
None of the
chemicals in this product are considered highly hazardous by OSHA.
CAS# 50-78-2 can be found on the following state right to
know lists: California, New Jersey, Florida, Pennsylvania, Minnesota,
The following statement(s) is(are) made in order to comply
with the California Safe Drinking Water Act: WARNING: This product contains
Acetylsalicylic acid (aspirin), a chemical known to the state of California to
cause birth defects or other reproductive harm. California No Significant Risk
Level: None of the chemicals in this product are listed.
European Labeling in
Accordance with EC Directives
R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes,
S 26 In case
of contact with eyes, rinse immediately
with plenty of water and seek
S 28 After contact with skin, wash immediately
WGK (Water Danger/Protection)
CAS# 50-78-2: 1
CAS# 50-78-2 is listed on Canada's DSL List. CAS# 50-78-2
is listed on Canada's DSL List.
This product has a WHMIS classification of
CAS# 50-78-2 is not listed on Canada's Ingredient Disclosure List.
CAS# 50-78-2: OEL-AUSTRALIA:TWA 5 mg/m3
OEL-BELGIUM:TWA 5 mg/m3 OE
L-DENMARK:TWA 5 mg/m3 OEL-THE NETHERLANDS:TWA 5
L 0.5 mg/m3 OEL-SWITZERLAND:TWA 5 mg/m3 OEL-UNITED
KINGDOM:TWA 5 mg/
m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN N
EW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #2 Date: 8/02/2000
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
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exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.