Material Safety Data Sheet
Acetylsalicylic Acid 99%

ACC# 00300
Section 1 - Chemical Product and Company Identification

MSDS Name: Acetylsalicylic Acid 99%
Catalog Numbers: AC158180000, AC158185000, S79881
Synonyms:
2-Acetoxybenzole acid, acenterine, acesal, aceticyl, acetisal, acetol, acetophen, asagran, aspirin, caprin
Company Identification:

              Fisher Scientific
              1 Reagent Lane
              Fair Lawn, NJ 07410
For information, call:
201-796-7100
Emergency Number:
201-796-7100
For CHEMTREC assistance, call:
800-424-9300
For International CHEMTREC assistance, call:
703-527-3887

Section 2 - Composition, Information on Ingredients

CAS# Chemical Name Percent EINECS/ELINCS
50-78-2 Acetylsalicylic acid (aspirin) 100 200-064-1

Hazard Symbols:
XN
Risk Phrases:
22 36/37/38

Section 3 - Hazards Identification

EMERGENCY OVERVIEW

Appearance: white. May cause skin irritation. Causes respiratory tract irritation. May cause respiratory and digestive tract irritation. May cause severe eye irritation and possible injury. Warning! Toxic. Harmful if swallowed.
Target Organs: Blood.


Potential Health Effects
Eye: May cause eye irritation and possible burns.
Skin: May cause skin irritation. Low hazard for usual industrial handling. Chronic ingestion may result in salicylism which is characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic strokes.
Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhibits platelet aggregation affecting bleeding time.
Inhalation: May cause respiratory tract irritation. Can produce anaphylactic shock with even small doses.
Chronic: Chronic ingestion may result in salicylism which is characterized by nausea, vomiting, gastrointestinal ulcers, and hemorrhagic strokes.

Section 4 - First Aid Measures


Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid.
Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician: Treat symptomatically and supportively.

Section 5 - Fire Fighting Measures


General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.

Section 6 - Accidental Release Measures


General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Avoid generating dusty conditions.

Section 7 - Handling and Storage


Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with skin and eyes. Avoid ingestion and inhalation.
Storage: Store in a cool, dry place. Store in a tightly closed container.

Section 8 - Exposure Controls, Personal Protection


Engineering Controls: Good general ventilation should be sufficient to control airborne levels.
Exposure Limits
Chemical Name ACGIH NIOSH OSHA - Final PELs
Acetylsalicylic acid (aspirin) 5 mg/m3 TWA 5 mg/m3 TWA none listed

OSHA Vacated PELs: Acetylsalicylic acid (aspirin): 5 mg/m3 TWA
Personal Protective Equipment
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin: Wear appropriate protective gloves to prevent skin exposure.
Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators: Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.

Section 9 - Physical and Chemical Properties


Physical State: Solid
Appearance: white
Odor: odorless
pH: Not available.
Vapor Pressure: Not applicable.
Vapor Density: Not available.
Evaporation Rate:Not applicable.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point:138 - 140 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Decomposition Temperature:Not available.
NFPA Rating: Not published.
Explosion Limits, Lower:Not available.
Upper: Not available.
Solubility: 2.5 G/L (15C)
Specific Gravity/Density:Not available.
Molecular Formula:C9H8O4
Molecular Weight:180.16

Section 10 - Stability and Reactivity


Chemical Stability: Stable.
Conditions to Avoid: Incompatible materials, strong oxidants.
Incompatibilities with Other Materials: Strong alkali, hydrolyzes in moist air, decomposes in hot water.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported.

Section 11 - Toxicological Information


RTECS#:
CAS# 50-78-2: VO0700000
LD50/LC50:
CAS# 50-78-2:
Oral, mouse: LD50 = 250 mg/kg;
Oral, rabbit: LD50 = 1010 mg/kg;
Oral, rat: LD50 = 200 mg/kg;
Carcinogenicity:
CAS# 50-78-2: Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA.
Epidemiology: No data available.
Teratogenicity: No data available.
Reproductive Effects: No data available.
Neurotoxicity: No data available.
Mutagenicity: No data available.
Other Studies: No data available.

Section 12 - Ecological Information

No information available.

Section 13 - Disposal Considerations

Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: None listed.

Section 14 - Transport Information

US DOT IATA RID/ADR IMO Canada TDG
Shipping Name: TOXIC SOLID, ORGANIC,N.O.S. (ACETYLSALICYLIC ACID) POISONOUS SOLID NOS (ACETYLSALICYLIC ACID)
Hazard Class: 6.1 6.1(9.2)
UN Number: UN2811 UN2811
Packing Group: III III

Section 15 - Regulatory Information

US FEDERAL

TSCA
CAS# 50-78-2 is listed on the TSCA inventory.
Health & Safety Reporting List
None of the chemicals are on the Health & Safety Reporting List.
Chemical Test Rules
None of the chemicals in this product are under a Chemical Test Rule.
Section 12b
None of the chemicals are listed under TSCA Section 12b.
TSCA Significant New Use Rule
None of the chemicals in this material have a SNUR under TSCA.
SARA

Section 302 (RQ)
None of the chemicals in this material have an RQ.
Section 302 (TPQ)
None of the chemicals in this product have a TPQ.
Section 313
No chemicals are reportable under Section 313.
Clean Air Act:
This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors.
Clean Water Act:
None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA.
OSHA:
None of the chemicals in this product are considered highly hazardous by OSHA.
STATE
CAS# 50-78-2 can be found on the following state right to know lists: California, New Jersey, Florida, Pennsylvania, Minnesota, Massachusetts.
The following statement(s) is(are) made in order to comply with the California Safe Drinking Water Act: WARNING: This product contains Acetylsalicylic acid (aspirin), a chemical known to the state of California to cause birth defects or other reproductive harm. California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols:
XN
Risk Phrases:

R 22 Harmful if swallowed.
R 36/37/38 Irritating to eyes, respiratory system
and skin.

Safety Phrases:

S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 28 After contact with skin, wash immediately
with...

WGK (Water Danger/Protection)

CAS# 50-78-2: 1
Canada
CAS# 50-78-2 is listed on Canada's DSL List. CAS# 50-78-2 is listed on Canada's DSL List.
This product has a WHMIS classification of D1B, D2B.
CAS# 50-78-2 is not listed on Canada's Ingredient Disclosure List.
Exposure Limits
CAS# 50-78-2: OEL-AUSTRALIA:TWA 5 mg/m3 OEL-BELGIUM:TWA 5 mg/m3 OE
L-DENMARK:TWA 5 mg/m3 OEL-THE NETHERLANDS:TWA 5 mg/m3 OEL-RUSSIA:STE
L 0.5 mg/m3 OEL-SWITZERLAND:TWA 5 mg/m3 OEL-UNITED KINGDOM:TWA 5 mg/
m3 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN N
EW ZEALAND, SINGAPORE, VIETNAM check ACGI TLV

Section 16 - Additional Information

MSDS Creation Date: 12/12/1997
Revision #2 Date: 8/02/2000
The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.