Material Safety Data
Section 1 - Chemical Product and Company
MSDS Name: Acetone
Numbers: S70090, S70091-1, A11-1, A11-20, A11-200, A11-4, A11S-4,
A16F-1GAL, A16P-4, A16S-20, A16S-4, A16S20001, A16S4LC, A18-1, A18-20, A18-200,
A18-4, A18-500, A18200001, A18200LC, A1820LC, A1820LOT003, A184LC, A184LOT001,
A18CU1300, A18J500, A18P-4, A18P4, A18RB115, A18RB19, A18RB200, A18RB50,
A18RS115, A18RS200, A18RS28, A18RS50, A18S-4, A18SK-4, A18SK4LC, A18SS-115,
A18SS-200, A18SS-30, A18SS-50, A19-1, A19-4, A20-1, A40-4, A404LOT007,
A404LOT008, A404LOT009, A928-4, A929-1, A929-4, A9294LC, A9294LOT001,
A9294LOT012, A9294LOT014, A9294LOT017, A9294LOT018, A9294LOT019, A9294LOT021,
A9294LOT022, A9294LOT024, A929J4, A929RS-115, A929RS-19, A929RS-200, A929RS-28,
A929RS-50, A929SS-115, A929SS-200, A929SS-28, A929SS-50, A930-4, A946-4,
A946FB200, A946RB115, A946RB19, A946RB200, A946RB50, A949-1, A949-4,
A9494LOT004, A949CU50, A949J4, A949LC, A949RS115, A949RS19, A949RS200, A949RS28,
A949RS50, A949SK-1, A949SK-4, A949SS-11, A949SS-115, A949SS-20, A949SS-200,
A949SS-30, A949SS-50, BP24011, BP240320, BP24034, BP2403500, BP2404, BPA18-4,
BPA946RB-115, BPA946RB-19, BPA946RB-200, BPA946RB-50, HC 300 1GAL, HC3001GAL,
NC9475452, NC9475553, NC9614315, NC9631882, NC9743229, S118016, S254CA4, S70091,
S70091HPLC, S70091SPEC, XXA181LI, XXA949U200LI
Dimethylformaldehyde; Dimethyl ketone; 2-Propanone; Pyroacetic acid; Pyroacetic
1 Reagent Lane
Lawn, NJ 07410
For information, call: 201-796-7100
For CHEMTREC assistance, call: 800-424-9300
For International CHEMTREC assistance, call: 703-527-3887
Section 2 -
Composition, Information on Ingredients
Symbols: XI F
Risk Phrases: 11 36 66 67
Section 3 - Hazards
Appearance: colourless. Flash Point: -4 deg F. Danger!
Causes eye and skin irritation. May cause central nervous system depression. May
cause liver and kidney damage. Causes respiratory tract irritation. Extremely
flammable liquid and vapor. Vapor may cause flash fire.
Organs: Kidneys, central nervous system, liver, respiratory system,
Eye: Produces irritation,
characterized by a burning sensation, redness, tearing, inflammation, and
possible corneal injury.
Skin: Exposure may cause
irritation characterized by redness, dryness, and inflammation.
Ingestion: May cause irritation of the digestive tract. May
cause central nervous system depression, kidney damage, and liver damage.
Symptoms may include: headache, excitement, fatigue, nausea, vomiting, stupor,
and coma. May cause liver and kidney damage. May cause central nervous system
depression, characterized by excitement, followed by headache, dizziness,
drowsiness, and nausea. Advanced stages may cause collapse, unconsciousness,
coma and possible death due to respiratory failure.
Inhalation: Inhalation of high concentrations may cause
central nervous system effects characterized by nausea, headache, dizziness,
unconsciousness and coma. Causes respiratory tract irritation. May cause liver
and kidney damage. May cause motor incoordination and speech abnormalities.
Chronic: Prolonged or repeated skin contact may cause
dermatitis. Chronic inhalation may cause effects similar to those of acute
Section 4 - First Aid
Eyes: Flush eyes with plenty of water for at least
15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid
Skin: Flush skin with plenty of soap and water
for at least 15 minutes while removing contaminated clothing and shoes. Get
medical aid if irritation develops or persists. Wash clothing before reuse.
Ingestion: Do NOT induce vomiting. If victim is conscious
and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an
unconscious person. Get medical aid immediately.
Inhalation: Get medical aid immediately. Remove from
exposure to fresh air immediately. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. Get medical aid. Do NOT use
mouth-to-mouth resuscitation. If breathing has ceased apply artificial
respiration using oxygen and a suitable mechanical device such as a bag and a
Notes to Physician: Treat symptomatically and
Section 5 - Fire
Information: Containers can build up pressure if exposed to heat and/or
fire. As in any fire, wear a self-contained breathing apparatus in
pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Vapors may form an explosive mixture with air. Vapors can travel to a source of
ignition and flash back. During a fire, irritating and highly toxic gases may be
generated by thermal decomposition or combustion. Use water spray to keep
fire-exposed containers cool. Extremely flammable liquid and vapor. Vapors may
be heavier than air. They can spread along the ground and collect in low or
confined areas. May be ignited by heat, sparks, and flame.
Extinguishing Media: For small fires, use dry chemical,
carbon dioxide, water spray or alcohol-resistant foam. For large fires, use
water spray, fog, or alcohol-resistant foam. Use water spray to cool
fire-exposed containers. Water may be ineffective. Do NOT use straight streams
of water. Cool containers with flooding quantities of water until well after
fire is out.
Section 6 -
Accidental Release Measures
Information: Use proper personal protective equipment as indicated in
Spills/Leaks: Absorb spill with inert material
(e.g. vermiculite, sand or earth), then place in suitable container. Avoid
runoff into storm sewers and ditches which lead to waterways. Wear appropriate
protective clothing to minimize contact with skin. Remove all sources of
ignition. Provide ventilation. A vapor suppressing foam may be used to reduce
vapors. Water spray may reduce vapor but may not prevent ignition in closed
spaces. Clean up residual material by washing area with a 2-5% solution of soda
Section 7 - Handling
Handling: Wash thoroughly after handling. Remove
contaminated clothing and wash before reuse. Use only in a well-ventilated area.
Ground and bond containers when transferring material. Avoid contact with eyes,
skin, and clothing. Empty containers retain product residue, (liquid and/or
vapor), and can be dangerous. Keep container tightly closed. Avoid contact with
heat, sparks and flame. Avoid ingestion and inhalation. Do not pressurize, cut,
weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or
Storage: Keep away from heat, sparks, and
flame. Keep away from sources of ignition. Store in a tightly closed container.
Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure
Controls, Personal Protection
Controls: Facilities storing or utilizing this material should be
equipped with an eyewash facility and a safety shower. Use adequate general or
local exhaust ventilation to keep airborne concentrations below the permissible
||500 ppm TWA; 750 ppm STEL
||250 ppm TWA; 590 mg/m3 TWA 2500 ppm IDLH (10
percent lower explosive level)
||1000 ppm TWA; 2400 mg/m3
OSHA Vacated PELs: Acetone:
750 ppm TWA; 1800 mg/m3 TWA; 1000 ppm STEL; 2400 mg/m3 STEL (The acetone STEL
does not apply to the cellulose
Eyes: Wear chemical goggles.
Skin: Wear appropriate protective gloves to prevent skin
Clothing: Wear appropriate protective clothing to
prevent skin exposure.
Respirators: Follow the OSHA respirator
regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a
NIOSH or European Standard EN 149 approved respirator when necessary.
Section 9 - Physical
and Chemical Properties
Vapor Pressure: 180 mm Hg
Evaporation Rate:7.7 (n-Butyl acetate=1)
Viscosity: Not available
Boiling Point: 133.2 deg F
Freezing/Melting Point:-139.6 deg F
Temperature: 869 deg F ( 465.00 deg C)
Flash Point: -4 deg F (
-20.00 deg C)
Decomposition Temperature:Not available.
Rating: (estimated) Health: 1; Flammability: 3; Reactivity: 0
Explosion Limits, Lower:2.5
Section 10 -
Stability and Reactivity
Stability: Stable at room temperature in closed containers under normal
storage and handling conditions.
Conditions to Avoid: High
temperatures, ignition sources, temperatures above 220°C.
Incompatibilities with Other Materials: Strong oxidizing agents,
strong acids, perchlorates, aliphatic amines, chromyl chloride,
hexachloromelamine, chromic anhydride, chloroform + alkali, potassium
Hazardous Decomposition Products: Carbon monoxide,
irritating and toxic fumes and gases, carbon dioxide.
Polymerization: Has not been reported.
Section 11 -
CAS# 67-64-1: AL3150000
Dermal, guinea pig: LD50 = >9400 uL/kg;
Draize test, rabbit,
eye: 20 mg Severe;
Draize test, rabbit, eye: 20 mg/24H Moderate;
test, rabbit, skin: 500 mg/24H Mild;
Inhalation, mouse: LC50 = 44
Inhalation, rat: LC50 = 50100 mg/m3/8H;
Oral, mouse: LD50 = 3
Oral, rabbit: LD50 = 5340 mg/kg;
Oral, rat: LD50 = 5800
- Not Classifiable as a Human Carcinogen
Epidemiology: No information
Teratogenicity: No information available.
Reproductive Effects: TDLo(Oral, rat) = 273 gm/kg;Reproductive -
Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology,
motility, and count).
Neurotoxicity: No information available.
Mutagenicity: Sex chromosome loss and nondisjunction(Yeast -
Saccharomyces cerevisiae) = 47600 ppm; Cytogenetic analysis(Rodent - hamster
Fibroblast)= 40 gm/L.
Other Studies: Standard Draize Test:
Administration onto the skin (human) = 500 mg/7days (Mild). Standard Draize
Test: Administrat ion onto the skin (rabbit) = 500 mg/24H (Mild). Standard D
raize Test( Eye, Rabbit) = 20 mg; Severe.
Section 12 -
Material Safety Data Sheet Brown trout: ; ; Rainbow trout LC50=5540 mg/L/96H
Sunfish (tap water), death at 14250 ppm/24H Mosquito fish (turbid water)
TLm=13000 ppm/48HCas# 67-64-1:LC50 (96Hr.) rainbow trout = 5540 mg/L; Static
conditions, 11-13 degrees CLC50 (96Hr) Fathead Minnow = 7280-8120 mg/L;
Flow-through ConditionsLC50 (96Hr) Bluegill = 8300 mg/L
Environmental: Volatilizes, leeches, and biodegrades when released to
soil. TERRESTRIAL FATE: If released on soil, acetone will both volatilize and
leach into the ground. Acetone readily biodegrades and there is evidence
suggesting that it biodegrades fairly rapidly in soils. AQUATIC FATE: If
released into water, acetone will probably biodegrade. It is readily
biodegradable in screening tests, although data from natural water are lacking.
It will also be lost due to volatilization (estimated half-life 20 hr from a
model river). Adsorption to sediment should not be significant.
Physical: ATMOSPHERIC FATE: In the atmosphere, acetone will be lost
by photolysis and reaction with photochemically produced hydroxyl radicals.
Half-life estimates from these combined processes are 79 and 13 days in January
and June, respectively, for an overall annual average of 22 days. Therefore
considerable dispersion should occur. Being miscible in water, wash out by rain
should be an important removal process. This process has been confirmed around
Lake Shinsei-ko in Japan. There acetone was found in the air and rain as well as
Other: Not expected to bioconcentrate in fish. he
recommended log octanol/water partition coefficient for acetone is -0.24 and
therefore its potential for bioconcentration in fish is negligible. One
experimental study of bioconcentration in adult haddock at 7-9 deg C (static
test), resulted in a BCF of 0.69.
Section 13 - Disposal
Chemical waste generators
must determine whether a discarded chemical is classified as a hazardous waste.
US EPA guidelines for the classification determination are listed in 40 CFR
Parts 261.3. Additionally, waste generators must consult state and local
hazardous waste regulations to ensure complete and accurate classification.
RCRA P-Series: None listed.
RCRA U-Series: CAS# 67-64-1:
waste number U002; (Ignitable waste).
Section 14 -
||FLASHPOINT -20 C|
Section 15 -
CAS# 67-64-1 is listed on the TSCA
Health & Safety Reporting List
None of the
chemicals are on the Health & Safety Reporting List.
None of the chemicals in this product are under a Chemical Test
CAS# 67-64-1: 4/12b
TSCA Significant New
None of the chemicals in this material have a SNUR under TSCA.
Section 302 (RQ)
CAS# 67-64-1: final RQ = 5000
pounds (2270 kg)
Section 302 (TPQ)
None of the chemicals in this
product have a TPQ.
CAS # 67-64-1: acute, chronic,
flammable, sudden release of pressure.
are reportable under Section 313.
Clean Air Act:
does not contain any hazardous air pollutants. This material does not contain
any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone
Clean Water Act:
None of the chemicals in this product
are listed as Hazardous Substances under the CWA. None of the chemicals in this
product are listed as Priority Pollutants under the CWA. None of the chemicals
in this product are listed as Toxic Pollutants under the CWA.
None of the chemicals in this product are considered highly
hazardous by OSHA.
CAS# 67-64-1 can be found on the
following state right to know lists: California, New Jersey, Florida,
Pennsylvania, Minnesota, Massachusetts.
California No Significant Risk
Level: None of the chemicals in this product are listed.
European Labeling in
Accordance with EC Directives
R 11 Highly flammable.
R 36 Irritating to eyes.
Repeated exposure may cause skin dryness or
R 67 Vapors may
cause drowsiness and dizziness.
S 16 Keep away
from sources of ignition - No
S 26 In case of contact with
eyes, rinse immediately
with plenty of water and seek medical advice.
9 Keep container in a well-ventilated place.
CAS# 67-64-1: 0
CAS# 67-64-1 is
listed on Canada's DSL List. CAS# 67-64-1 is listed on Canada's DSL List.
This product has a WHMIS classification of B2, D2B.
CAS# 67-64-1 is
listed on Canada's Ingredient Disclosure List.
CAS# 67-64-1: OEL-AUSTRALIA:TWA 500 ppm (1185 mg/m3);STEL 1000 ppm
OEL-AUSTRIA:TWA 750 ppm (1780 mg/m3) OEL-BELGIUM:TWA 750 ppm (1780
/m3);STEL 1000 pp OEL-CZECHOSLOVAKIA:TWA 800 mg/m3;STEL 4000 mg/m3
EL-DENMARK:TWA 250 ppm (600 mg/m3) OEL-FINLAND:TWA 500 ppm (1200
3);STEL 625 ppm (1500 mg/m3) OEL-FRANCE:TWA 750 ppm (1800 mg/m3)
-GERMANY:TWA 1000 ppm (2400 mg/m3) OEL-HUNGARY:TWA 600 mg/m3;STEL
0 mg/m3 OEL-INDIA:TWA 750 ppm (1780 mg/m3);STEL 1000 ppm (2375
OEL-JAPAN:TWA 200 ppm (470 mg/m3) OEL-THE NETHERLANDS:TWA 750 ppm (
1780 mg/m3) JAN9 OEL-THE PHILIPPINES:TWA 1000 ppm (2400 mg/m3)
OLAND:TWA 200 mg/m3 OEL-RUSSIA:TWA 200 ppm;STEL 200 mg/m3
:TWA 250 ppm (600 mg/m3);STEL 500 ppm (1200 mg/m3)
A 750 ppm (1780 mg/m3) OEL-TURKEY:TWA 1000 ppm (2400
ED KINGDOM:TWA 750 ppm (1810 mg/m3);STEL 1250 ppm OEL IN
LOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND,
VIETNAM check ACGI TLV
Section 16 -
MSDS Creation Date:
Revision #9 Date: 3/19/2001
The information above is
believed to be accurate and represents the best information currently available
to us. However, we make no warranty of merchantability or any other warranty,
express or implied, with respect to such information, and we assume no liability
resulting from its use. Users should make their own investigations to determine
the suitability of the information for their particular purposes. In no event
shall Fisher be liable for any claims, losses, or damages of any third party or
for lost profits or any special, indirect, incidental, consequential or
exemplary damages, howsoever arising, even if Fisher has been advised of the
possibility of such damages.